(Hexadecyloxy)trimethylsilane

Base Information

• Chemical Name: (Hexadecyloxy)trimethylsilane
• CAS No.: 6221-90-5
• Molecular Formula: C19H42 O Si
• Molecular Weight: 314.627
• DSSTox Substance ID: DTXSID20211272
• Nikkaji Number: J543.035F
• Wikidata: Q83086140
• Mol file: 6221-90-5.mol

Synonyms:1-Trimethylsiloxyhexadecane;(HEXADECYLOXY)TRIMETHYLSILANE;Silane, (hexadecyloxy)trimethyl-;6221-90-5;1-Hexadecanol, O-TMS;1-Hexadecanol, TMS derivative;SCHEMBL5701643;DTXSID20211272;JTMICAOGVLZKRG-UHFFFAOYSA-N;(Hexadecyloxy)(trimethyl)silane #

Chemical Property of (Hexadecyloxy)trimethylsilane

Chemical Property:

• Vapor Pressure: 5.68E-05mmHg at 25°C
• Boiling Point: 357.3°C at 760 mmHg
• Flash Point: 177.1°C
• Density: 0.818g/cm³
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 16
• Exact Mass: 314.300492493
• Heavy Atom Count: 21
• Complexity: 198

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCO[Si](C)(C)C

Technology Process of (Hexadecyloxy)trimethylsilane

There total 6 articles about (Hexadecyloxy)trimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

trimethylsilyl acetate (2754-27-0) + 1-Hexadecanol (36653-82-4,124-29-8) → 1-hexadecanol, trimethylsilyl ether (6221-90-5)

Guidance literature:

With triethylamine; In neat (no solvent); at 20 ℃; for 2h;

DOI:10.1055/a-1654-2211

Reference yield: 96.0%

chloro-trimethyl-silane (75-77-4) + 1-Hexadecanol (36653-82-4,124-29-8) → 1-hexadecanol, trimethylsilyl ether (6221-90-5)

Guidance literature:

With iodine; In 1,2-dichloro-ethane; at 46 - 50 ℃; for 0.0333333h; microwave irradiation;

DOI:10.1081/scc-120026335

Reference yield: 95.0%

1-Hexadecanol (36653-82-4,124-29-8) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → 1-hexadecanol, trimethylsilyl ether (6221-90-5)

Guidance literature:

With lithium perchlorate; silica gel; In dichloromethane; at 20 ℃; for 0.0833333h;

DOI:10.1016/j.jorganchem.2005.11.005

upstream raw materials:

chloro-trimethyl-silane

1-Hexadecanol

trimethylsilylazide

1,1,1,3,3,3-hexamethyl-disilazane

Downstream raw materials:

n-hexadecylaldehyde

1-Hexadecanol