(R)-tert-butyl 2-(tert-butoxycarbonylamino) -3-(4-hydroxyphenyl)propanoate

Base Information

Chemical Name:(R)-tert-butyl 2-(tert-butoxycarbonylamino) -3-(4-hydroxyphenyl)propanoate
CAS No.:1414025-67-4
Molecular Formula:C₁₈H₂₇NO₅
Molecular Weight:337.416
Hs Code.:

Synonyms:(R)-tert-butyl 2-(tert-butoxycarbonylamino) -3-(4-hydroxyphenyl)propanoate

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Chemical Property of (R)-tert-butyl 2-(tert-butoxycarbonylamino) -3-(4-hydroxyphenyl)propanoate

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Technology Process of (R)-tert-butyl 2-(tert-butoxycarbonylamino) -3-(4-hydroxyphenyl)propanoate

There total 2 articles about (R)-tert-butyl 2-(tert-butoxycarbonylamino) -3-(4-hydroxyphenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 87553-74-0
(R)-tert-butyl 2-amino-3-(4-hydroxyphenyl)propanoate

: 1414025-67-4
(R)-tert-butyl 2-(tert-butoxycarbonylamino) -3-(4-hydroxyphenyl)propanoate

Guidance literature:: With triethylamine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 2h;

Reference yield: 52.0%

: 70642-86-3
N-(tert-butoxycarbonyl)-D-tyrosine

: 83766-88-5
2-tert-butoxypyridine

: 1414025-67-4
(R)-tert-butyl 2-(tert-butoxycarbonylamino) -3-(4-hydroxyphenyl)propanoate

Guidance literature:: With boron trifluoride diethyl etherate; In toluene; at 20 ℃; for 0.5h;
DOI:10.1016/j.tet.2018.05.050

Reference yield: 81.0%

: 2373-51-5
chloro-methylsulfanyl-methane

: 1414025-67-4
(R)-tert-butyl 2-(tert-butoxycarbonylamino) -3-(4-hydroxyphenyl)propanoate

: 1417188-25-0
tert-butyl N-(tert-butoxycarbonyl)-O-[(methylsulfanyl)methyl]-D-tyrosinate

Guidance literature:: With potassium tert-butylate; sodium iodide; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 3h; Cooling with ice;