Technology Process of 2-<2-Methoxy-3-(butenyl)phenyl>-4,4-dimethyl-2-oxazoline
There total 4 articles about 2-<2-Methoxy-3-(butenyl)phenyl>-4,4-dimethyl-2-oxazoline which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium tert-butylate / tert-butyl alcohol / 24 h / 90 °C
2: n-butyllithium; N,N,N,N,-tetramethylethylenediamine / 1) in dry ether at reflux for 1h 2) CO2 as a continous stream for 1h
3: thionyl chloride
With
n-butyllithium; thionyl chloride; N,N,N,N,-tetramethylethylenediamine; potassium tert-butylate;
In
tert-butyl alcohol;
DOI:10.1021/jo00317a027
- Guidance literature:
-
Multi-step reaction with 4 steps
1: n-butyllithium; N,N,N,N,-tetramethylethylenediamine / 1) in dry ether at reflux for 1h 2) -22 deg C overnight
2: potassium tert-butylate / tert-butyl alcohol / 24 h / 90 °C
3: n-butyllithium; N,N,N,N,-tetramethylethylenediamine / 1) in dry ether at reflux for 1h 2) CO2 as a continous stream for 1h
4: thionyl chloride
With
n-butyllithium; thionyl chloride; N,N,N,N,-tetramethylethylenediamine; potassium tert-butylate;
In
tert-butyl alcohol;
DOI:10.1021/jo00317a027
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1) TMEDA, n-BuLi / 1) in dry ether at reflux for 1h 2) CO2 as a continous stream for 1h
2: 1) SOCl2
With
n-butyllithium; thionyl chloride; N,N,N,N,-tetramethylethylenediamine;
DOI:10.1021/jo00317a027
