methyl (2-(chloromethyl)-4-(perfluoropropane-2-yl)phenyl)carbamate

Base Information

• Chemical Name: methyl (2-(chloromethyl)-4-(perfluoropropane-2-yl)phenyl)carbamate
• CAS No.: 872217-42-0
• Molecular Formula: C₁₂H₉ClF₇NO₂
• Molecular Weight: 367.651
• Mol file: 872217-42-0.mol

Synonyms:methyl (2-(chloromethyl)-4-(perfluoropropane-2-yl)phenyl)carbamate

Chemical Property of methyl (2-(chloromethyl)-4-(perfluoropropane-2-yl)phenyl)carbamate

Chemical Property:

Purity/Quality:

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Technology Process of methyl (2-(chloromethyl)-4-(perfluoropropane-2-yl)phenyl)carbamate

There total 6 articles about methyl (2-(chloromethyl)-4-(perfluoropropane-2-yl)phenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenylcarbamic acid methyl ester (273735-80-1) → methyl (2-(chloromethyl)-4-(perfluoropropane-2-yl)phenyl)carbamate (872217-42-0)

Guidance literature:

With sulfuryl dichloride; 2,2’-azobis(4-methoxy-2,4-dimethyl)valeronitrile; In chlorobenzene; at 35 ℃; for 2h; Product distribution / selectivity;

Reference yield:

methyl N-[2-(chloromethyl)phenyl]carbamate (117550-42-2) + 2-bromo-1,1,1,2,3,3,3-heptafluoropropane (422-77-5) → methyl (2-(chloromethyl)-4-(perfluoropropane-2-yl)phenyl)carbamate (872217-42-0)

Guidance literature:

With sodium dithionite; tetra(n-butyl)ammonium hydrogensulfate; sodium carbonate; In tert-butyl methyl ether; water; at 20 - 25 ℃; for 8h;

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + methyl 4-(perfluoropropan-2-yl)phenylcarbamate → methyl (2-(chloromethyl)-4-(perfluoropropane-2-yl)phenyl)carbamate (872217-42-0)

Guidance literature:

With hydrogenchloride; zinc(II) chloride; In water; 1,2-dichloro-ethane; at 60 - 65 ℃; for 10h;

upstream raw materials:

2-methyl-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenylcarbamic acid methyl ester

methyl N-[2-(chloromethyl)phenyl]carbamate

2-bromo-1,1,1,2,3,3,3-heptafluoropropane

formaldehyd