4-[2-(tert-butyldimethylsilanyloxy)-2-methylpropoxy]-3,5-dimethylbenzonitrile

Base Information

Chemical Name:4-[2-(tert-butyldimethylsilanyloxy)-2-methylpropoxy]-3,5-dimethylbenzonitrile
CAS No.:924300-39-0
Molecular Formula:C₁₉H₃₁NO₂Si
Molecular Weight:333.546
Hs Code.:

Synonyms:4-[2-(tert-butyldimethylsilanyloxy)-2-methylpropoxy]-3,5-dimethylbenzonitrile

Suppliers and Price of 4-[2-(tert-butyldimethylsilanyloxy)-2-methylpropoxy]-3,5-dimethylbenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[2-(tert-butyldimethylsilanyloxy)-2-methylpropoxy]-3,5-dimethylbenzonitrile

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[2-(tert-butyldimethylsilanyloxy)-2-methylpropoxy]-3,5-dimethylbenzonitrile

There total 2 articles about 4-[2-(tert-butyldimethylsilanyloxy)-2-methylpropoxy]-3,5-dimethylbenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: 924300-38-9
4-(2-hydroxy-2-methylpropoxy)-3,5-dimethyl benzonitrile

: 18162-48-6
tert-butyldimethylsilyl chloride

: 924300-39-0
4-[2-(tert-butyldimethylsilanyloxy)-2-methylpropoxy]-3,5-dimethylbenzonitrile

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; at 20 ℃; for 72h;

Reference yield:

: 4198-90-7
3,5-dimethyl-4-hydroxybenzonitrile

: 924300-39-0
4-[2-(tert-butyldimethylsilanyloxy)-2-methylpropoxy]-3,5-dimethylbenzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / ethanol; water / 24 h / 20 °C / Reflux

2: 1H-imidazole / N,N-dimethyl-formamide / 72 h / 20 °C / Inert atmosphere

With 1H-imidazole; potassium carbonate; In ethanol; water; N,N-dimethyl-formamide;

Reference yield: 37.0%

: 884502-04-9
2,4-dimethoxy-N,6-dimethylbenzamide

: 924300-39-0
4-[2-(tert-butyldimethylsilanyloxy)-2-methylpropoxy]-3,5-dimethylbenzonitrile

: 924300-40-3
3-{4-[2-[(tert-butyl dimethylsilyl)oxy]-2-methylpropoxy]-3,5-dimethylphenyl}-6,8-dimethoxy-2H-isoquinolin-1-one

Guidance literature:: 2,4-dimethoxy-N,6-dimethylbenzamide; With n-butyllithium; In tetrahydrofuran; hexane; at -10 - 0 ℃; for 1.16667h;

4-[2-(tert-butyldimethylsilanyloxy)-2-methylpropoxy]-3,5-dimethylbenzonitrile; In tetrahydrofuran; hexane; at -50 - 20 ℃; for 1h;