N-(cyclopropanecarbonyl)benzamide

Base Information

• Chemical Name: N-(cyclopropanecarbonyl)benzamide
• CAS No.: 756488-67-2
• Molecular Formula: C11H11 N O2
• Molecular Weight: 189.214
• DSSTox Substance ID: DTXSID10478357
• Wikidata: Q82311697
• Mol file: 756488-67-2.mol

Synonyms:756488-67-2;DTXSID10478357;AG-H-01531

Chemical Property of N-(cyclopropanecarbonyl)benzamide

Chemical Property:

• PSA: 49.66000
• LogP: 1.92780
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 189.078978594
• Heavy Atom Count: 14
• Complexity: 240

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC1C(=O)NC(=O)C2=CC=CC=C2

Technology Process of N-(cyclopropanecarbonyl)benzamide

There total 2 articles about N-(cyclopropanecarbonyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N-phenylcyclopropanecarboximidamide (1342132-54-0) + benzil (134-81-6) → N-phenyl benzoyl amide (93-98-1,5705-51-1) + cyclopropanecarboxylic acid benzoylamide (756488-67-2)

Guidance literature:

With vanadyl(IV) sulfate hydrate; water; In N,N-dimethyl-formamide; at 70 ℃; for 18h;

DOI:10.1021/acs.joc.7b00950

Reference yield: 88.0%

N-(cyclopropyl)methylbenzamide (756488-62-7) → cyclopropanecarboxylic acid benzoylamide (756488-67-2)

Guidance literature:

With acetic anhydride; periodic acid; chromium(VI) oxide; In acetonitrile; at 0 ℃; for 1h;

DOI:10.1039/b404823g

Reference yield:

chloro-trimethyl-silane (75-77-4) + benzaldehyde (100-52-7) + cyclopropanecarboxylic acid benzoylamide (756488-67-2) → C21H25NO3Si

Guidance literature:

chloro-trimethyl-silane; benzaldehyde; cyclopropanecarboxylic acid benzoylamide; With sodium iodide; scandium tris(trifluoromethanesulfonate); In dichloromethane; at 0 ℃; for 48h; Inert atmosphere;

With triethylamine; In dichloromethane; at 0 - 25 ℃;

DOI:10.1021/ol800401g

upstream raw materials:

N-(cyclopropyl)methylbenzamide

N-phenylcyclopropanecarboximidamide

benzil