(S)-N-(2-benzoylphenyl)-1-(3,4-dimethylbenzyl)pyrrolidine-2-carboxamide hydrochloride

Base Information

Chemical Name:(S)-N-(2-benzoylphenyl)-1-(3,4-dimethylbenzyl)pyrrolidine-2-carboxamide hydrochloride
CAS No.:884659-57-8
Molecular Formula:C₂₇H₂₉N₂O₂*Cl
Molecular Weight:448.992
Hs Code.:

Synonyms:(S)-N-(2-benzoylphenyl)-1-(3,4-dimethylbenzyl)pyrrolidine-2-carboxamide hydrochloride

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Chemical Property of (S)-N-(2-benzoylphenyl)-1-(3,4-dimethylbenzyl)pyrrolidine-2-carboxamide hydrochloride

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Technology Process of (S)-N-(2-benzoylphenyl)-1-(3,4-dimethylbenzyl)pyrrolidine-2-carboxamide hydrochloride

There total 8 articles about (S)-N-(2-benzoylphenyl)-1-(3,4-dimethylbenzyl)pyrrolidine-2-carboxamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: (S)-1-(3,4-Dimethyl-benzyl)-pyrrolidine-2-carboxylic acid; hydrochloride

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 884659-57-8
(S)-N-(2-benzoylphenyl)-1-(3,4-dimethylbenzyl)pyrrolidine-2-carboxamide hydrochloride

Guidance literature:: With phosphorus pentachloride; In dichloromethane; at 20 ℃; for 15h;
DOI:10.1007/s11172-006-0276-1

Reference yield:

: C₃₀H₃₁N₃NiO₄

: 111-42-2
2,2'-iminobis[ethanol]

: 884659-57-8
(S)-N-(2-benzoylphenyl)-1-(3,4-dimethylbenzyl)pyrrolidine-2-carboxamide hydrochloride

: (S)-2-amino-3-[bis(2-hydroxyethyl)amino]propionic acid hydrochloride

Guidance literature:: C₃₀H₃₁N₃NiO₄; With acetic anhydride; sodium carbonate; In acetonitrile; at 25 - 70 ℃;

2,2'-iminobis[ethanol]; With sodium hydroxide; In acetonitrile; at 50 ℃; for 8.5h;

With hydrogenchloride; water; In ethanol;
DOI:10.1016/j.tetasy.2010.10.015

Reference yield:

: C₃₀H₃₁N₃NiO₄

: 100-46-9
benzylamine

: 884659-57-8
(S)-N-(2-benzoylphenyl)-1-(3,4-dimethylbenzyl)pyrrolidine-2-carboxamide hydrochloride

: 119830-32-9
(S)-2-amino-3-(benzylamino)propionic acid

Guidance literature:: C₃₀H₃₁N₃NiO₄; With acetic anhydride; sodium carbonate; In acetonitrile; at 25 - 70 ℃;

benzylamine; With sodium hydroxide; In acetonitrile; at 50 ℃; for 2.5h;

With hydrogenchloride; water; In ethanol;
DOI:10.1016/j.tetasy.2010.10.015