benzo[d]oxazol-2-yl(4-methoxy phenyl)methanone

Base Information

• Chemical Name: benzo[d]oxazol-2-yl(4-methoxy phenyl)methanone
• CAS No.: 1258498-75-7
• Molecular Formula: C₁₅H₁₁NO₃
• Molecular Weight: 253.257
• Mol file: 1258498-75-7.mol

Synonyms:benzo[d]oxazol-2-yl(4-methoxy phenyl)methanone

Chemical Property of benzo[d]oxazol-2-yl(4-methoxy phenyl)methanone

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of benzo[d]oxazol-2-yl(4-methoxy phenyl)methanone

There total 21 articles about benzo[d]oxazol-2-yl(4-methoxy phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

C21H17NO5S → benzo[d]oxazol-2-yl(4-methoxy phenyl)methanone (1258498-75-7)

Guidance literature:

With potassium carbonate; In methanol; at 20 ℃; for 1h;

DOI:10.1039/c4cc02425g

Reference yield: 83.0%

benzoxazole (273-53-0,29791-96-6) + 4-methoxy-benzoyl chloride (100-07-2) → benzo[d]oxazol-2-yl(4-methoxy phenyl)methanone (1258498-75-7)

Guidance literature:

With dmap; triethylamine; In acetonitrile; at 80 ℃; for 24h; Sealed tube; Inert atmosphere;

DOI:10.1055/s-0033-1339858

Reference yield: 81.0%

benzo[d]oxazole-2-carbaldehyde (62667-25-8) + di(4-methoxyphenyl)iodonium triflate (1429318-45-5) → benzo[d]oxazol-2-yl(4-methoxy phenyl)methanone (1258498-75-7)

Guidance literature:

With 2-pentafluorophenyl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate; dmap; isopropyl alcohol; In dichloromethane; at -40 ℃; for 2.5h; Inert atmosphere;

DOI:10.1021/ja400051d

upstream raw materials:

benzoxazole

carbon monoxide

para-iodoanisole

benzo[d]oxazole-2-carbaldehyde