ACETYL-TRANS-RESVERATROL

Base Information

• Chemical Name: ACETYL-TRANS-RESVERATROL
• CAS No.: 63366-83-6
• Molecular Formula: C₁₈H₁₈O₄
• Molecular Weight: 298.339
• Mol file: 63366-83-6.mol

Synonyms:Phenol,4-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-, acetate (9CI);Phenol, 4-[2-(3,5-dimethoxyphenyl)ethenyl]-,acetate, (E)-;Actyl resveratrol;

Chemical Property of ACETYL-TRANS-RESVERATROL

Chemical Property:

• Melting Point: 123 - 126 °C
• Boiling Point: 504.803 °C at 760 mmHg
• Flash Point: 221.436 °C
• PSA: 78.90000
• Density: 1.241 g/cm³
• LogP: 3.63290

Purity/Quality:

98%,99%, ^*data from raw suppliers

Acetyl-trans-resveratrol >98%,Standard References Grade ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ACETYL-TRANS-RESVERATROL

There total 12 articles about ACETYL-TRANS-RESVERATROL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

p-acetoxystyrene (2628-16-2) + 3,5-dimethoxybenzenediazonium tetrafluoroborate (72470-95-2) → (E)-1-(4'-acetoxyphenyl)-2-(3,5-dimethoxyphenyl)ethene (18259-14-8,63366-83-6)

Guidance literature:

With palladium diacetate; sodium acetate; In benzonitrile; at 25 ℃; for 3h;

DOI:10.1016/j.tetlet.2008.07.087

Reference yield: 93.7%

p-acetoxystyrene (2628-16-2) + 1-iodo-3,5-dimethoxybenzene (25245-27-6) → (E)-1-(4'-acetoxyphenyl)-2-(3,5-dimethoxyphenyl)ethene (18259-14-8,63366-83-6)

Guidance literature:

With tetrabutylammomium bromide; potassium acetate; palladium diacetate; In N,N-dimethyl-formamide; at 80 ℃; for 5h; Inert atmosphere; Sealed tube;

DOI:10.1016/j.ejmech.2017.05.025

Reference yield: 84.0%

p-acetoxystyrene (2628-16-2) + 3,5-dimethoxyphenylboronic acid (192182-54-0) → (E)-1-(4'-acetoxyphenyl)-2-(3,5-dimethoxyphenyl)ethene (18259-14-8,63366-83-6)

Guidance literature:

With dichloro bis(acetonitrile) palladium(II); oxygen; sodium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 3h; Reagent/catalyst; Solvent; Catalytic behavior;

DOI:10.1016/j.bmcl.2016.07.018

upstream raw materials:

p-acetoxystyrene

3,5-dimethoxybenzoyl chloride

3,5-dimethoxystyrene

3,5-dimethoxybenzenediazonium tetrafluoroborate

Downstream raw materials:

4'-Acetylresveratrol

3,5-dimethoxy-4'-hydroxy-trans-stilbene

3,5-di-O-methyldihydroresveratrol

Refernces

• 1、 Liang, Jian-Hua,Yang, Liang,Wu, Si,Liu, Si-Si,Cushman, Mark,Tian, Jing,Li, Nuo-Min,Yang, Qing-Hu,Zhang, He-Ao,Qiu, Yun-Jie,Xiang, Lin,Ma, Cong-Xuan,Li, Xue-Meng,Qing, Hong. "Discovery of efficient stimulators for adult hippocampal neurogenesis based on scaffolds in dragon's blood". supporting information. p. 382 - 392. Retrieved 2017/05/19.
• 2、 Uzura, Saori,Sekine-Suzuki, Emiko,Nakanishi, Ikuo,Sonoda, Motohiro,Tanimori, Shinji. "A facile and rapid access to resveratrol derivatives and their radioprotective activity". supporting information. p. 3886 - 3891. Retrieved 2016/08/01.