3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-5-hydroxy-2,2-bis(2-hydroxyethyl)pentanoic acid

Base Information

Chemical Name:3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-5-hydroxy-2,2-bis(2-hydroxyethyl)pentanoic acid
CAS No.:518044-40-1
Molecular Formula:C13H19 N O7
Molecular Weight:301.296
Hs Code.:
DSSTox Substance ID:DTXSID10703873
Mol file:518044-40-1.mol

Synonyms:Maleimide-PEG3-CH2CH2COOH;DTXSID10703873;AMY21423;FT-0604026;3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-5-hydroxy-2,2-bis(2-hydroxyethyl)pentanoic acid

Suppliers and Price of 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-5-hydroxy-2,2-bis(2-hydroxyethyl)pentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

ChemScene
Maleimido-tri(ethyleneglycol)-propionicacid
100mg
$ 300.00

BroadPharm
Mal-PEG3-acid 98%
100 MG
$ 320.00

BroadPharm
Mal-PEG3-acid 98%
5 G
$ 4800.00

BroadPharm
Mal-PEG3-acid 98%
1 G
$ 1350.00

BroadPharm
Mal-PEG3-acid 98%
500 MG
$ 850.00

American Custom Chemicals Corporation
MAL-PEG3-ACID 95.00%
100MG
$ 525.00

Acrotein
Mal-PEG3-CH2CH2COOH 97%
0.5g
$ 293.33

Total 18 raw suppliers

Chemical Property of 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-5-hydroxy-2,2-bis(2-hydroxyethyl)pentanoic acid

Chemical Property:

Boiling Point:491.4±40.0 °C(Predicted)
PKA:4.28±0.10(Predicted)
PSA：135.37000
Density:1.293±0.06 g/cm3(Predicted)
LogP:-1.56390
XLogP3:-2.1
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:9
Exact Mass:301.11615195
Heavy Atom Count:21
Complexity:422

Purity/Quality:

97% ^*data from raw suppliers

Maleimido-tri(ethyleneglycol)-propionicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=O)N(C1=O)C(CCO)C(CCO)(CCO)C(=O)O
Description Mal-PEG3-acid is a PEG linker containing a maleimide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Technology Process of 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-5-hydroxy-2,2-bis(2-hydroxyethyl)pentanoic acid

There total 4 articles about 3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-5-hydroxy-2,2-bis(2-hydroxyethyl)pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%