ethyl-(α,α-dideuterio-benzyl)-ether

Base Information

• Chemical Name: ethyl-(α,α-dideuterio-benzyl)-ether
• CAS No.: 120992-49-6
• Molecular Formula: C₉H₁₂O
• Molecular Weight: 138.178
• Mol file: 120992-49-6.mol

Synonyms:ethyl-(α,α-dideuterio-benzyl)-ether

Chemical Property of ethyl-(α,α-dideuterio-benzyl)-ether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl-(α,α-dideuterio-benzyl)-ether

There total 3 articles about ethyl-(α,α-dideuterio-benzyl)-ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1-dideuteriophenylmethanol (21175-64-4) → ethyl-(α,α-dideuterio-benzyl)-ether (120992-49-6)

Guidance literature:

With Petroleum ether; Einleiten von HBr und Erwaermen des erhaltenen α,α-Dideuterio-benzylbromids mit Natriumaethylat in Aethanol;

DOI:10.1021/ja01604a036

Reference yield:

benzoic acid ethyl ester (93-89-0,99341-95-4) → ethyl-(α,α-dideuterio-benzyl)-ether (120992-49-6)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlD₄; diethyl ether

2: petroleum ether / Einleiten von HBr und Erwaermen des erhaltenen α,α-Dideuterio-benzylbromids mit Natriumaethylat in Aethanol

With lithium aluminium deuteride; diethyl ether; Petroleum ether;

DOI:10.1021/ja01604a036

Reference yield:

[1',1'-2H2]benzyl bromide (51271-29-5) + sodium ethanolate (141-52-6) → ethyl-(α,α-dideuterio-benzyl)-ether (120992-49-6)

Guidance literature:

In N,N-dimethyl-formamide; at 25 ℃; for 1h;

DOI:10.1021/jo00376a006

upstream raw materials:

1,1-dideuteriophenylmethanol

[1',1'-2H₂]benzyl bromide

sodium ethanolate

benzoic acid ethyl ester

Downstream raw materials:

propane

ethene

n-propane-d1

benzyl alcohol-d1

Refernces