51271-29-5 Usage
Description
BENZYL-ALPHA,ALPHA-D2 BROMIDE, with the CAS number 51271-29-5, is an isotopically labeled research compound that is utilized in various scientific studies and experiments. It is a deuterated version of benzyl bromide, which means it contains deuterium atoms instead of regular hydrogen atoms. This characteristic makes it a valuable tool for researchers to investigate the effects of isotopic substitution on chemical reactions and molecular properties.
Uses
Used in Chemical Research:
BENZYL-ALPHA,ALPHA-D2 BROMIDE is used as a research compound for studying the impact of isotopic labeling on chemical reactions and molecular behavior. The deuterium atoms in this compound can help researchers understand the differences in reaction rates, energy barriers, and other properties when compared to the non-deuterated version.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, BENZYL-ALPHA,ALPHA-D2 BROMIDE is used as a key intermediate in the synthesis of various drugs and drug candidates. The deuterium labeling can provide insights into the metabolic pathways and pharmacokinetics of these compounds, potentially leading to the development of more effective and safer medications.
Used in Material Science:
BENZYL-ALPHA,ALPHA-D2 BROMIDE is employed as a component in the development of novel materials with specific properties. The isotopic substitution can influence the material's stability, reactivity, and other characteristics, making it a valuable tool for researchers in material science.
Used in Environmental Studies:
In environmental science, BENZYL-ALPHA,ALPHA-D2 BROMIDE can be used to study the fate and transport of pollutants in the environment. The deuterium labeling allows for easier detection and tracking of these compounds, providing valuable information on their behavior and potential impacts on ecosystems.
Used in Analytical Chemistry:
BENZYL-ALPHA,ALPHA-D2 BROMIDE is utilized as a reference material or internal standard in various analytical techniques, such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. The deuterium labeling can improve the accuracy and precision of these measurements, enabling researchers to obtain more reliable results.
Check Digit Verification of cas no
The CAS Registry Mumber 51271-29-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,2,7 and 1 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 51271-29:
(7*5)+(6*1)+(5*2)+(4*7)+(3*1)+(2*2)+(1*9)=95
95 % 10 = 5
So 51271-29-5 is a valid CAS Registry Number.
51271-29-5Relevant articles and documents
Selective C-H Allylic Oxygenation of Cycloalkenes and Terpenoids Photosensitized by [Cu(Xantphos)(neoc)]BF4
Kallitsakis, Michael G.,Gioftsidou, Dimitra K.,Tzani, Marina A.,Angaridis, Panagiotis A.,Terzidis, Michael A.,Lykakis, Ioannis N.
, p. 13503 - 13513 (2021/09/13)
We present herein for the first time the use of the [Cu(Xantphos)(neoc)]BF4 as a photocatalyst for the selective C-H allylic oxygenation of cycloalkenes into the corresponding allylic hydroperoxides or alcohols in the presence of molecular oxygen. The proposed methodology affords the products at good yields and has also been applied successfully to several bioactive terpenoids, such as geraniol, linalool, β-citronellol, and phytol. A mechanistic study involving also kinetic isotope effects (KIEs) supports the proposed singlet oxygen-mediated reaction. On the basis of the high chemoselectivity and yields and the fast and clean reaction processes observed, the present catalytic system, [Cu(Xantphos)(neoc)]BF4, has also been applied to the synthesis, at a laboratory scale, of the cis-Rose oxide, a well-known perfumery ingredient used in rose and geranium perfumes.
Iron-Catalyzed Amination of Strong Aliphatic C(sp3)-H Bonds
Das, Sandip Kumar,Roy, Satyajit,Khatua, Hillol,Chattopadhyay, Buddhadeb
, p. 16211 - 16217 (2020/10/26)
A concept for intramolecular denitrogenative C(sp3)-H amination of 1,2,3,4-tetrazoles bearing unactivated primary, secondary, and tertiary C-H bonds is discovered. This catalytic amination follows an unprecedented metalloradical activation mechanism. The utility of the method is showcased with the short synthesis of a bioactive molecule. Moreover, an initial effort has been embarked on for the enantioselective C(sp3)-H amination through the catalyst design. Collectively, this study underlines the development of C(sp3)-H bond functionalization chemistry that should find wide application in the context of drug discovery and natural product synthesis.
Mechanistic analysis of oxidative C-H cleavages using inter- and intramolecular kinetic isotope effects
Jung, Hyung Hoon,Floreancig, Paul E.
experimental part, p. 10830 - 10836 (2010/02/28)
A series of monodeuterated benzylic and allylic ethers were subjected to oxidative carbon-hydrogen bond cleavage to determine the impact of structural variation on intramolecular kinetic isotope effects in DDQ-mediated cyclization reactions. These values