Ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride

Base Information

• Chemical Name: Ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride
• CAS No.: 548472-48-6
• Molecular Formula: C13H19NO3.HCl
• Molecular Weight: 273.76
• Hs Code.: 2925290090
• Mol file: 548472-48-6.mol

Synonyms:Ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride

Chemical Property of Ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride

Chemical Property:

• Vapor Pressure: 2.76E-05mmHg at 25°C
• Boiling Point: 352.1°C at 760 mmHg
• Flash Point: 166.7°C
• PSA: 51.54000
• LogP: 3.74600
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl2-isopropoxy-4-methoxybenzimidatehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride

There total 2 articles about Ethyl 2-isopropoxy-4-methoxybenzimidate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-isopropoxy-4-methoxy-benzonitrile (548472-47-5) → 2-isopropoxy-4-methoxybenzimidic acid ethyl ester hydrochloride (548472-48-6)

Guidance literature:

In diethyl ether; ethanol;

Reference yield:

2-isopropoxy-4-methoxy-benzonitrile (548472-47-5) + ethanol (64-17-5) → 2-isopropoxy-4-methoxybenzimidic acid ethyl ester hydrochloride (548472-48-6)

Guidance literature:

With hydrogenchloride; at 20 ℃; for 7h;

Reference yield: 73.0%

2-isopropoxy-4-methoxybenzimidic acid ethyl ester hydrochloride (548472-48-6) + meso-1,2-bis(4-chlorophenyl)ethylenediamine (86212-34-2,98674-96-5) + sodium hydrogencarbonate (144-55-8) → trans-4,5-Bis-(4-chloro-phenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-1H-imidazole (844692-35-9)

Guidance literature:

With triethylamine; In methanol; diethyl ether; ethanol; dichloromethane; pentane;

upstream raw materials:

2-isopropoxy-4-methoxy-benzonitrile

ethanol

Downstream raw materials:

trans-4,5-Bis-(4-chloro-phenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-1H-imidazole

Refernces

• 1、 -. "Cis-imidazolines". . . Retrieved 2008/06/13.