1-(2-bromoethoxy)-3-fluorobenzene

Base Information

• Chemical Name: 1-(2-bromoethoxy)-3-fluorobenzene
• CAS No.: 85262-57-3
• Molecular Formula: C₈H₈BrFO
• Molecular Weight: 219.053
• Mol file: 85262-57-3.mol

Synonyms:1-(2-bromoethoxy)-3-fluorobenzene

Chemical Property of 1-(2-bromoethoxy)-3-fluorobenzene

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

1-(2-Bromoethoxy)-3-fluorobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(2-bromoethoxy)-3-fluorobenzene

There total 4 articles about 1-(2-bromoethoxy)-3-fluorobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

3-fluorophenol (372-20-3) + ethylene dibromide (106-93-4) → 1-(2-bromoethoxy)-3-fluorobenzene (85262-57-3)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; at 60 ℃;

DOI:10.1016/j.ejmech.2012.07.043 DOI:10.1016/j.ejmech.2012.07.043

Reference yield: 38.0%

→ 1-(2-bromoethoxy)-3-fluorobenzene (85262-57-3)

Guidance literature:

With sodium hydroxide; In water; at 130 ℃; for 16h;

Reference yield:

3-fluorophenol (372-20-3) + argon + ethylene dibromide (106-93-4) → 1-(2-bromoethoxy)-3-fluorobenzene (85262-57-3)

Guidance literature:

With potassium carbonate; In diethyl ether; acetonitrile;

upstream raw materials:

3-fluorophenol

ethylene dibromide

Downstream raw materials:

(S)-4-(2-{4-[2-(3-fluoro-phenoxy)-ethoxy]-phenyl}-ethyl)-4-hydroxymethyl-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester

N-({1-[2-(3-fluorophenoxy)ethyl]piperidin-4-yl}methyl)thiophene-2-sulfonamide

2-(3-fluorophenoxy)ethanamine

Refernces

• 1、 Bhagat, Shweta,Arfeen, Minhajul,Adane, Legesse,Singh, Savita,Singh, Prati Pal,Chakraborti, Asit K.,Bharatam, Prasad V.. "Guanylthiourea derivatives as potential antimalarial agents: Synthesis, in?vivo and molecular modelling studies". . p. 339 - 348. Retrieved 2017/05/04.
• 2、 -. "DOPAMINE D2 RECEPTOR LIGANDS". Page/Page column 118; 119; 121. . Retrieved 2016/07/05.