Methyl alpha-D-ribofuranoside

Base Information

• Chemical Name: Methyl alpha-D-ribofuranoside
• CAS No.: 52485-92-4
• Molecular Formula: C6H12O5
• Molecular Weight: 164.158
• Hs Code.: 2932190090
• Nikkaji Number: J504.909A
• Wikidata: Q63409834
• Mol file: 52485-92-4.mol

Synonyms:Methyl alpha-D-ribofuranoside;52485-92-4;(2R,3S,4R,5S)-2-(HYDROXYMETHYL)-5-METHOXYOXOLANE-3,4-DIOL;Methyl pentofuranoside #;Methylalfa-D-ribofuranoside;Methyl alfa-D-ribofuranoside;Methyl-I(2)-D-ribofuranosid;SCHEMBL338232;Methyl-.alpha.-d-ribofuranoside;Q63409834;(2R,3S,4R,5S)-2-(Hydroxymethyl)-5-methoxytetrahydrofuran-3,4-diol

Chemical Property of Methyl alpha-D-ribofuranoside

Chemical Property:

• Boiling Point: 348.7±42.0 °C(Predicted)
• PKA: 13.14±0.70(Predicted)
• PSA: 79.15000
• Density: 1.40±0.1 g/cm3(Predicted)
• LogP: -1.92820
• XLogP3: -1.6
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 164.06847348
• Heavy Atom Count: 11
• Complexity: 128

Purity/Quality:

97% ^*data from raw suppliers

Methyl a-D-ribofuranoside ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1C(C(C(O1)CO)O)O
• Isomeric SMILES: CO[C@@H]1[C@@H]([C@@H]([C@H](O1)CO)O)O

Technology Process of Methyl alpha-D-ribofuranoside

There total 47 articles about Methyl alpha-D-ribofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + D-Ribose (532-20-7,613-83-2,7261-25-8,7687-39-0,13221-22-2,14795-83-6,15761-67-8,20074-49-1,25545-03-3,25545-04-4,32445-75-3,34436-17-4,36441-93-7,36468-53-8,37110-85-3,37388-49-1,38029-69-5,40461-77-6,40461-89-0,41546-19-4,41546-20-7,41546-21-8,41546-26-3,41546-29-6,41546-30-9,41546-31-0,126872-16-0,131064-98-7) → methyl ribofuranoside (1824-96-0,1824-97-1,3795-68-4,3795-69-5,4229-54-3,5531-18-0,7473-45-2,13039-63-9,13039-64-0,13039-65-1,13039-67-3,22416-73-5,22861-09-2,25129-51-5,52485-92-4,52689-55-1,52689-56-2,56607-40-0,72880-70-7,79083-42-4,86782-30-1,86782-31-2,89615-03-2,89673-67-6,89707-99-3,102045-32-9,135910-17-7)

Guidance literature:

With Dowex-50 (H+); at 4 ℃;

DOI:10.1002/ejoc.200600182

Reference yield: 100.0%

methanol (67-56-1) + D-ribose (50-69-1) → methyl ribofuranoside (1824-96-0,1824-97-1,3795-68-4,3795-69-5,4229-54-3,5531-18-0,7473-45-2,13039-63-9,13039-64-0,13039-65-1,13039-67-3,22416-73-5,22861-09-2,25129-51-5,52485-92-4,52689-55-1,52689-56-2,56607-40-0,72880-70-7,79083-42-4,86782-30-1,86782-31-2,89615-03-2,89673-67-6,89707-99-3,102045-32-9,135910-17-7)

Guidance literature:

With Dowex-50w (H⁺); at 0 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.bmc.2010.07.005

Reference yield: 79.0%

methanol (67-56-1) + C30H26N4O8 (189129-08-6) → methyl ribofuranoside (1824-96-0,1824-97-1,3795-68-4,3795-69-5,4229-54-3,5531-18-0,7473-45-2,13039-63-9,13039-64-0,13039-65-1,13039-67-3,22416-73-5,22861-09-2,25129-51-5,52485-92-4,52689-55-1,52689-56-2,56607-40-0,72880-70-7,79083-42-4,86782-30-1,86782-31-2,89615-03-2,89673-67-6,89707-99-3,102045-32-9,135910-17-7)

Guidance literature:

With sodium methylate; for 0.75h; Ambient temperature; other reagent, reaction time;

DOI:10.1080/07328319708002528

upstream raw materials:

methanol

D-ribose

D-Ribose

(2R,3R,4R,5S)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)-5-methoxytetrahydrofuran

Downstream raw materials:

methyl 2,3,5-tri-O-benzoyl-α-D-ribofuranoside

methanol

D-Ribose

5'-amino-5'-deoxy-1'-O-methyl-D-ribose