6-BOC-3,6-DIAZABICYCLO[3.2.0]HEPTANE

Base Information

Chemical Name:6-BOC-3,6-DIAZABICYCLO[3.2.0]HEPTANE
CAS No.:122848-57-1
Molecular Formula:C10H18 N2 O2
Molecular Weight:198.265
Hs Code.:2933990090
Mol file:122848-57-1.mol

Synonyms:3,6-Diazabicyclo[3.2.0]heptane-6-carboxylicacid tert-butyl ester

Suppliers and Price of 6-BOC-3,6-DIAZABICYCLO[3.2.0]HEPTANE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
tert-Butyl3,6-Diazabicyclo[3.2.0]heptane-6-carboxylate
100mg
$ 350.00

Synthonix
cis-3,6-Diazabicyclo[3.2.0]heptane-6-carboxylicacidtert-butylester 97.0%
10g
$ 3670.00

SynQuest Laboratories
tert-Butyl 3,6-diazabicyclo[3.2.0]heptane-6-carboxylate 97.0%
250 mg
$ 590.00

SynQuest Laboratories
tert-Butyl 3,6-diazabicyclo[3.2.0]heptane-6-carboxylate 97.0%
1 g
$ 1690.00

Matrix Scientific
cis-3,6-Diazabicyclo[3.2.0]heptane-6-carboxylicacidtert-butylester 97.0%
1g
$ 1304.00

Crysdot
tert-Butyl3,6-diazabicyclo[3.2.0]heptane-6-carboxylate 95+%
1g
$ 540.00

Chemenu
tert-butyl3,6-diazabicyclo[3.2.0]heptane-6-carboxylate 95%
1g
$ 390.00

American Custom Chemicals Corporation
6-BOC-3,6-DIAZABICYCLO(3.2.0)HEPTANE 95.00%
5G
$ 23322.45

American Custom Chemicals Corporation
6-BOC-3,6-DIAZABICYCLO(3.2.0)HEPTANE 95.00%
1G
$ 6224.06

Ambeed
tert-Butyl3,6-diazabicyclo[3.2.0]heptane-6-carboxylate 97%
1g
$ 650.00

Total 29 raw suppliers

Chemical Property of 6-BOC-3,6-DIAZABICYCLO[3.2.0]HEPTANE

Chemical Property:

Refractive Index:1.5
Boiling Point:276.4±13.0 °C(Predicted)
PKA:10.65±0.20(Predicted)
PSA：41.57000
Density:1.104±0.06 g/cm3(Predicted)
LogP:1.09180
Storage Temp.:2-8°C(protect from light)

Purity/Quality:

99%, ^*data from raw suppliers

tert-Butyl3,6-Diazabicyclo[3.2.0]heptane-6-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-BOC-3,6-DIAZABICYCLO[3.2.0]HEPTANE

There total 10 articles about 6-BOC-3,6-DIAZABICYCLO[3.2.0]HEPTANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.1%

: 370880-79-8
3-benzyl 6-(tert-butyl)-3,6-diazabicyclo[3.2.0]heptane-3,6-dicarboxylate

: 122848-57-1
tert-butyl-3,6-diazabicyclo[3,2,0]heptane-6-carboxylate

Guidance literature:: With hydrogen; 5% Pd(II)/C(eggshell); In methanol; for 1.5h; under 775.743 Torr;

Reference yield:

: 1017789-40-0,252770-09-5,255823-06-4
3-amino-4-hydroxymethyl-pyrrolidine-1-carboxylic acid benzyl ester

: 122848-57-1
tert-butyl-3,6-diazabicyclo[3,2,0]heptane-6-carboxylate

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium hydrogencarbonate / ethanol; water; pentan-1-ol / 15 h / 20 °C / Inert atmosphere

2.1: triethylamine / dichloromethane / 22.33 h / 0 - 20 °C / Inert atmosphere

3.1: trifluoroacetic acid / dichloromethane / 20 h

3.2: pH ~ 12

4.1: sodium hydroxide / ethanol; water / 1.5 h / 60 °C

5.1: sodium hydroxide / ethanol; water / 0.67 h / 20 °C

6.1: hydrogen / 5% Pd(II)/C(eggshell) / methanol / 1.5 h / 775.74 Torr

With hydrogen; sodium hydrogencarbonate; triethylamine; trifluoroacetic acid; sodium hydroxide; 5% Pd(II)/C(eggshell); In methanol; ethanol; dichloromethane; pentan-1-ol; water;

Reference yield:

: 1255099-67-2,246510-67-8
3-tert-butoxycarbonylamino-4-hydroxymethyl-pyrrolidine-1-carboxylic acid benzyl ester

: 122848-57-1
tert-butyl-3,6-diazabicyclo[3,2,0]heptane-6-carboxylate

Guidance literature:: Multi-step reaction with 5 steps

1.1: triethylamine / dichloromethane / 22.33 h / 0 - 20 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 20 h

2.2: pH ~ 12

3.1: sodium hydroxide / ethanol; water / 1.5 h / 60 °C

4.1: sodium hydroxide / ethanol; water / 0.67 h / 20 °C

5.1: hydrogen / 5% Pd(II)/C(eggshell) / methanol / 1.5 h / 775.74 Torr

With hydrogen; triethylamine; trifluoroacetic acid; sodium hydroxide; 5% Pd(II)/C(eggshell); In methanol; ethanol; dichloromethane; water;