2,4-Dichloro-6-fluoroquinazoline

Base Information

Chemical Name:2,4-Dichloro-6-fluoroquinazoline
CAS No.:134517-57-0
Molecular Formula:C8H3Cl2FN2
Molecular Weight:217.03
Hs Code.:2933599590
DSSTox Substance ID:DTXSID50586541
Wikidata:Q72466350
Mol file:134517-57-0.mol

Synonyms:2,4-dichloro-6-fluoroquinazoline;134517-57-0;MFCD09954884;QUINAZOLINE, 2,4-DICHLORO-6-FLUORO-;4-Dichloro-6-fluoroquinazoline;2?4-dichloro-6-fluoroquinazoline;2,4-dichloro-6-fluoro-quinazoline;SCHEMBL1991118;DTXSID50586541;6-fluoro-2,4-dichloroquinazoline;VLPYLGGGYDUVJN-UHFFFAOYSA-N;AKOS015853535;AB55585;CS-W001036;DS-15021;SY007266;2 pound not4-Dichloro-6-fluoroquinazoline;DB-063026;A2856;AM20020414;W-205440

Suppliers and Price of 2,4-Dichloro-6-fluoroquinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4-Dichloro-6-fluoroquinazoline
100mg
$ 60.00

TRC
2,4-Dichloro-6-fluoroquinazoline
50mg
$ 45.00

SynQuest Laboratories
2,4-Dichloro-6-fluoroquinazoline
5 g
$ 364.00

SynQuest Laboratories
2,4-Dichloro-6-fluoroquinazoline
1 g
$ 114.00

Matrix Scientific
2,4-Dichloro-6-fluoroquinazoline 97%
250mg
$ 38.00

Matrix Scientific
2,4-Dichloro-6-fluoroquinazoline 97%
1g
$ 74.00

Matrix Scientific
2,4-Dichloro-6-fluoroquinazoline 97%
5g
$ 218.00

Crysdot
2,4-Dichloro-6-fluoroquinazoline 97+%
25g
$ 743.00

Crysdot
2,4-Dichloro-6-fluoroquinazoline 97+%
10g
$ 390.00

Chemenu
2,4-Dichloro-6-fluoroquinazoline 95%
10g
$ 362.00

Total 57 raw suppliers

Chemical Property of 2,4-Dichloro-6-fluoroquinazoline

Chemical Property:

Vapor Pressure:0.43mmHg at 25°C
Refractive Index:1.644
Boiling Point:201.7 °C at 760 mmHg
PKA:-1.09±0.30(Predicted)
Flash Point:75.8 °C
PSA：25.78000
Density:1.571 g/cm³
LogP:3.07570
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:215.9657317
Heavy Atom Count:13
Complexity:193

Purity/Quality:

99% ^*data from raw suppliers

2,4-Dichloro-6-fluoroquinazoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1F)C(=NC(=N2)Cl)Cl

Technology Process of 2,4-Dichloro-6-fluoroquinazoline

There total 9 articles about 2,4-Dichloro-6-fluoroquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.8%

: 32315-10-9
bis(trichloromethyl) carbonate

: 61272-77-3
2-cyano-4-fluoroaniline

: 134517-57-0
2,4-dichloro-6-fluoro-quinazoline

Guidance literature:: bis(trichloromethyl) carbonate; With triethylamine; Triphenylphosphine oxide; In chlorobenzene; at 20 ℃; for 0.5h; Cooling with ice;

2-cyano-4-fluoroaniline; In chlorobenzene; at 120 ℃; for 10h;
DOI:10.3987/COM-12-12466

Reference yield: 86.0%

: 88145-90-8
6-fluoro-2,4-dioxo-1,2,3,4-tetrahydroquinazoline

: 134517-57-0
2,4-dichloro-6-fluoro-quinazoline

Guidance literature:: With phosphorus pentachloride; trichlorophosphate; for 9h; Reflux;

Reference yield: 85.0%

: 319-64-2
5-fluoro-β-(hydroxylimino)isatin

: 134517-57-0
2,4-dichloro-6-fluoro-quinazoline

Guidance literature:: With bis(trichloromethyl) carbonate; Tris(4-methoxyphenyl)phosphine oxide; In chlorobenzene; at 120 ℃; for 6h;
DOI:10.1080/10426507.2020.1782910