Dimethyl [(3-methoxyphenyl)methyl]phosphonate

Base Information

Chemical Name:Dimethyl [(3-methoxyphenyl)methyl]phosphonate
CAS No.:135203-54-2
Molecular Formula:C10H15O4P
Molecular Weight:230.2
Hs Code.:
DSSTox Substance ID:DTXSID50564602
Wikidata:Q82449375
Mol file:135203-54-2.mol

Synonyms:135203-54-2;Dimethyl [(3-methoxyphenyl)methyl]phosphonate;1-(dimethoxyphosphorylmethyl)-3-methoxybenzene;Dimethyl(3-methoxybenzyl)phosphonate;Dimethyl(3-Methoxybenzyl)phosphonate, 98 per cent;DIMETHYL (3-METHOXYBENZYL)PHOSPHONATE;DTXSID50564602;Dimethyl 3-methoxybenzylphosphonate;MFCD09838881;AKOS017343676;1-(dimethoxyphosphorylmethyl)-3-methoxy-benzene

Suppliers and Price of Dimethyl [(3-methoxyphenyl)methyl]phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DIMETHYL(3-METHOXYBENZYL)PHOSPHONATE 95.00%
5MG
$ 499.66

Total 3 raw suppliers

Chemical Property of Dimethyl [(3-methoxyphenyl)methyl]phosphonate

Chemical Property:

Boiling Point:334.9±25.0 °C(Predicted)
PSA：54.57000
Density:1.153±0.06 g/cm3(Predicted)
LogP:2.68110
XLogP3:0.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:230.07079595
Heavy Atom Count:15
Complexity:224

Purity/Quality:

97% ^*data from raw suppliers

DIMETHYL(3-METHOXYBENZYL)PHOSPHONATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1)CP(=O)(OC)OC

Technology Process of Dimethyl [(3-methoxyphenyl)methyl]phosphonate

There total 3 articles about Dimethyl [(3-methoxyphenyl)methyl]phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1350846-02-4
(3-methoxyphenyl)methyl methyl carbonate

: 868-85-9
Dimethyl phosphite

: 135203-54-2
dimethyl <(3-methoxyphenyl)methyl>phosphonate

Guidance literature:: With bis(η3-allyl-μ-chloropalladium(II)); bis[2-(diphenylphosphino)phenyl] ether; In N,N-dimethyl-formamide; at 100 ℃; for 24h; Inert atmosphere; Sealed tube;
DOI:10.1246/cl.170901

Reference yield:

: 6971-51-3
3-methoxybenzyl alcohol

: 121-45-9
phosphorous acid trimethyl ester

: 135203-54-2
dimethyl <(3-methoxyphenyl)methyl>phosphonate

Guidance literature:: With zinc(II) iodide; In toluene; at 110 ℃; for 15h; Inert atmosphere;
DOI:10.1021/jo401716p

Reference yield:

: 6971-51-3
3-methoxybenzyl alcohol

: 135203-54-2
dimethyl <(3-methoxyphenyl)methyl>phosphonate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / Inert atmosphere

2: bis(η3-allyl-μ-chloropalladium(II)); bis[2-(diphenylphosphino)phenyl] ether / N,N-dimethyl-formamide / 24 h / 100 °C / Inert atmosphere; Sealed tube

With bis(η3-allyl-μ-chloropalladium(II)); triethylamine; bis[2-(diphenylphosphino)phenyl] ether; In N,N-dimethyl-formamide;
DOI:10.1246/cl.170901