3-(4-ISOBUTYL-PHENYL)-PROPAN-1-OL

Base Information

• Chemical Name: 3-(4-ISOBUTYL-PHENYL)-PROPAN-1-OL
• CAS No.: 147598-21-8
• Molecular Formula: C13H20 O
• Molecular Weight: 192.301
• Mol file: 147598-21-8.mol

Synonyms:3-(4-ISOBUTYL-PHENYL)-PROPAN-1-OL

Chemical Property of 3-(4-ISOBUTYL-PHENYL)-PROPAN-1-OL

Chemical Property:

• Boiling Point: 299.4±9.0 °C(Predicted)
• PKA: 15.08±0.10(Predicted)
• PSA: 20.23000
• Density: 0.949±0.06 g/cm3(Predicted)
• LogP: 2.81000

Purity/Quality:

98%min ^*data from raw suppliers

3-[4-(2-methylpropyl)phenyl]propan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-[4-(2-Methylpropyl)phenyl]propan-1-ol is used in process for the hydrogenation in the presence of transition metal complex comprising a tridentate or bisdentate ligand.

Technology Process of 3-(4-ISOBUTYL-PHENYL)-PROPAN-1-OL

There total 4 articles about 3-(4-ISOBUTYL-PHENYL)-PROPAN-1-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(E)-ethyl 3-(4-isobutylphenyl)acrylate (1256636-24-4) → 3-(4-isobutylphenyl)propan-1-ol (147598-21-8)

Guidance literature:

With RuCl₂(2-(diphenylphosphino)-N-(2-(n-butylthio)ethyl)ethanamine)PPh₃; potassium methanolate; hydrogen; In tetrahydrofuran; at 105 ℃; for 16h; under 37503.8 Torr; Autoclave;

Reference yield: 82.0%

(E)-ethyl 3-(4-isobutylphenyl)acrylate (1256636-24-4) → C15H22O2 (230287-81-7) + 3-(4-isobutylphenyl)propan-1-ol (147598-21-8)

Guidance literature:

With RuCl₂(2-(diphenylphosphino)-N-(2-(n-butylthio)ethyl)ethanamine)PPh₃; potassium methanolate; hydrogen; In tetrahydrofuran; at 105 ℃; for 16h; under 37503.8 Torr; Autoclave;

Reference yield:

carbon monoxide (201230-82-2) + p-isobutylstyrene (63444-56-4) → 2-(4-isobutylphenyl)propan-1-ol (36039-36-8) + 3-(4-isobutylphenyl)propan-1-ol (147598-21-8)

Guidance literature:

With sodium tetrahydroborate; zwitterionic rhodium ν⁶-tetraphenylborate; isopropyl alcohol; In dichloromethane; at 100 ℃; for 22h; under 25857.4 Torr; Yield given. Yields of byproduct given;

DOI:10.1039/c39910000233

upstream raw materials:

carbon monoxide

p-isobutylstyrene

formaldehyd

(E)-ethyl 3-(4-isobutylphenyl)acrylate

Refernces

• 1、 Morimoto, Tsumoru,Fujii, Tetsuji,Miyoshi, Kota,Makado, Gouki,Tanimoto, Hiroki,Nishiyama, Yasuhiro,Kakiuchi, Kiyomi. "Accessible protocol for asymmetric hydroformylation of vinylarenes using formaldehyde". supporting information. p. 4632 - 4636. Retrieved 2015/04/27.
• 2、 Zhou, Jian-Qiang,Alper, Howard. "Reductive Carbonylation of Alkenes using Zwitterionic Rhodium Complexes as Catalysts". . p. 233 - 234. Retrieved 2007/10/02.