63444-56-4

Basic information

• Product Name: 4-ISOBUTYLSTYRENE
• Synonyms: 4-ISOBUTYLSTYRENE;1-Isobutyl-4-vinylbenzene;1-Vinyl-4-isobutylbenzene;1-(4'-Isobutylphenyl)ethene;1-Ethenyl-4-(2-Methylpropyl)benzene;p-Isobutylstyrene;Ibuprofen Impurity (4-Isobutylstyrene)
• CAS NO: 63444-56-4
• Molecular Formula: C₁₂H₁₆
• Molecular Weight: 160.25544
• EINECS: 604-604-1
• Product Categories: Aromatics;Intermediates
• Mol File: 63444-56-4.mol
• Article Data: 22

Chemical Properties

• Melting Point: -36.9°C (estimate)
• Boiling Point: 227℃
• Flash Point: 85℃
• Appearance: /
• Density: 0.882
• Refractive Index: 1.5218
• CAS DataBase Reference: 4-ISOBUTYLSTYRENE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ISOBUTYLSTYRENE(63444-56-4)
• EPA Substance Registry System: 4-ISOBUTYLSTYRENE(63444-56-4)

Safety Data

• Hazardous Substances Data: 63444-56-4(Hazardous Substances Data)

Usage

Uses

p-Isobutylstyrene is a phototransformation product of Ibuprofen (I140000) and Ketoprofen (K200800) in aqueous solutions. p-Isobutylstyrene is also used in the preparation of copolymer series for migration imaging applications.

Upstream product

• 124-38-9 carbon dioxide 
• 62049-65-4 S-(-)-1-(-)-[4-isobutylphenyl]-chloroethane 
• 608119-17-1 l-(4-isobutylphenyl)ethanesulfonic acid 
• 74-85-1 ethene 
• 2051-99-2 1-bromo-4-isobutylbenzene 
• 40150-98-9 4-(2-methyl-1-propyl)benzaldehyde 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 108-05-4 vinyl acetate 
• 15687-27-1 ibuprofen 
• 78-77-3 Isobutyl bromide 
• 18120-63-3 (4-vinylphenyl)magnesium bromide 
• 19493-09-5 Methylenetriphenylphosphorane 
• 38861-78-8 1-(4-isobutyl-phenyl)-ethanone 
• 132980-23-5 1-(4-Isobutylphenyl)ethylisocyanid 

Downstream Products

• 58609-73-7 2-(4-isobutylphenyl)propanenitrile 
• 110773-62-1 S-2-(p-isobutylphenyl)propionaldehyde 
• 114937-27-8 (2R)-2-<4-(2-Methylpropyl)phenyl>propanal 
• 40764-03-2 3-(4-i-butyl-phenyl)-propanal 
• 15687-27-1 ibuprofen 
• 51146-56-6 (S)-ibuprofen 
• 51146-57-7 (R)-ibuprofene 
• 85711-18-8 1-isobutyl-4-[(R)-1-methylallyl]benzene 
• 85711-17-7 1-isobutyl-4-[(S)-1-methylallyl]benzene 
• 1263162-32-8 1-(4-isobutylphenyl)ethane-1,2-diol 
• 61566-34-5 (+/-)-ibuprofen methyl ester 
• 63753-05-9 methyl 3-(4-isobutylphenyl)propanoate 
• 65322-85-2 3-(4'-isobutylphenyl)propionic acid 

Relevant articles and documents

Nickel-Catalyzed Reductive Cross-Coupling of Aryl Bromides with Vinyl Acetate in Dimethyl Isosorbide as a Sustainable Solvent

A nickel-catalyzed reductive cross-coupling has been achieved using (hetero)aryl bromides and vinyl acetate as the coupling partners. This mild, applicable method provides a reliable access to a variety of vinyl arenes, heteroarenes, and benzoheterocycles, which should expand the chemical space of precursors to fine chemicals and polymers. Importantly, a sustainable solvent, dimethyl isosorbide, is used, making this protocol more attractive from the point of view of green chemistry.

Photocatalytic carbocarboxylation of styrenes with CO2for the synthesis of γ-aminobutyric esters

Metal-free photoredox-catalyzed carbocarboxylation of various styrenes with carbon dioxide (CO2) and amines to obtain γ-aminobutyric ester derivatives has been developed (up to 91% yield, 36 examples). The radical anion of (2,3,4,6)-3-benzyl-2,4,5,6-tetra(9H-carbazol-9-yl)benzonitrile (4CzBnBN) possessing a high reduction potential (?1.72 Vvs.saturated calomel electrode (SCE)) easily reduces both electron-donating and electron-withdrawing group-substituted styrenes.

A process for the preparation and synthetic ChondriamideA and ChondriamideC method (by machine translation)

The invention provides a process for the preparation of synthetic Chondriamide A and Chondriamide C and method, wherein the invention provides a process for the preparation, including: formula (I) compounds of structure, palladium catalyst, phosphorus ligand, alkali and organic solvent at room temperature the illumination reaction, formula (II) structure obtained olefin; wherein through the selection of a particular phosphorus ligand; make the method of the invention can be under the photocatalysis, room temperature to realize high-efficient catalytic conversion, and the mild reaction conditions, simple operation, in line with the development of green environment-friendly chemical requirements, and the range of choice of substrate and functional group compatibility has more universal, and has outstanding chemical selectivity; and the method can be successfully applied to complex molecular introducing carbon-carbon double bond to the programme, to optimize a part of the drug molecular synthesis strategy, improve the synthesis efficiency, reduce the cost, with industrial synthetic value and prospects. (by machine translation)