4-(Piperidin-4-YL)benzoic acid hydrochloride

Base Information

Chemical Name:4-(Piperidin-4-YL)benzoic acid hydrochloride
CAS No.:149353-84-4
Molecular Formula:C₁₂H₁₅NO₂*ClH
Molecular Weight:241.718
Hs Code.:2933399090
DSSTox Substance ID:DTXSID20598550
Mol file:149353-84-4.mol

Synonyms:149353-84-4;4-(PIPERIDIN-4-YL)BENZOIC ACID HYDROCHLORIDE;4-(4'-Carboxyphenyl)piperidine HCl;4-piperidin-4-ylbenzoic acid hydrochloride;4-(4'-Carboxyphenyl)piperidine hydrochloride;4-(4'-Carboxyphenyl)piperidine.HCl;4-Piperidin-4-ylbenzoic acid;hydrochloride;MFCD08460726;Benzoic acid, 4-(4-piperidinyl)-, hydrochloride (1:1);4-(Piperidin-4-yl)benzoicacidhydrochloride;SCHEMBL4774320;AMY7574;DTXSID20598550;VVWYZHFWAUQTKI-UHFFFAOYSA-N;4-(4-Piperidinyl)Benzoic Acid HCl;4-(Piperidin-4-yl)benzoic acid HCl;AKOS015909002;AC-6309;AC-6310;DS-13779;SY114156;DB-063799;4-(4''-CARBOXYPHENYL)PIPERIDINE HCL;4-(4-carboxyphenyl)-piperidine-hydrochloride;4-Piperidin-4-yl-benzoic acid hydrochloride;CS-0060222;VU0494906-1;A26693;EN300-235001;J-513825;F2189-0634;4-(Piperidin-4-yl)benzoic acid hydrochloride, AldrichCPR;4-(Piperidin-4-yl)benzoic acid--hydrogen chloride (1/1)

Suppliers and Price of 4-(Piperidin-4-YL)benzoic acid hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Piperidin-4-yl)benzoicacidhydrochloride
250mg
$ 285.00

Crysdot
4-(Piperidin-4-yl)benzoicacidhydrochloride 95+%
1g
$ 257.00

Chemenu
4-(piperidin-4-yl)benzoicacidhydrochloride 95%
1g
$ 243.00

American Custom Chemicals Corporation
4-PIPERIDIN-4-YL-BENZOIC ACID HYDROCHLORIDE 95.00%
5G
$ 1423.77

Ambeed
4-(Piperidin-4-yl)benzoicacidhydrochloride 98+%
5g
$ 223.00

Ambeed
4-(Piperidin-4-yl)benzoicacidhydrochloride 98+%
1g
$ 62.00

Ambeed
4-(Piperidin-4-yl)benzoicacidhydrochloride 98+%
250mg
$ 25.00

Alichem
4-(Piperidin-4-yl)benzoicacidhydrochloride
5g
$ 891.80

Alichem
4-(Piperidin-4-yl)benzoicacidhydrochloride
1g
$ 267.80

AK Scientific
4-(Piperidin-4-yl)benzoicacidhydrochloride
250mg
$ 93.00

Total 24 raw suppliers

Chemical Property of 4-(Piperidin-4-YL)benzoic acid hydrochloride

Chemical Property:

Refractive Index: ">
Boiling Point:399.7 °C at 760 mmHg
Flash Point:195.5 °C
PSA：49.33000
LogP:2.98260
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:241.0869564
Heavy Atom Count:16
Complexity:216

Purity/Quality:

97% ^*data from raw suppliers

4-(Piperidin-4-yl)benzoicacidhydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCCC1C2=CC=C(C=C2)C(=O)O.Cl

Technology Process of 4-(Piperidin-4-YL)benzoic acid hydrochloride

There total 5 articles about 4-(Piperidin-4-YL)benzoic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 4-(1-acetyl-piperidin-4-yl)-benzoic acid

: 149353-84-4
4-(4-carboxyphenyl)-piperidine-hydrochloride

Guidance literature:: With hydrogenchloride; In water; at 140 ℃; for 18h; Inert atmosphere;

Reference yield:

: 79-37-8
oxalyl dichloride

: 32245-87-7
1-(4-Phenyl-piperidin-1-yl)-ethanone

: 149353-84-4
4-(4-carboxyphenyl)-piperidine-hydrochloride

Guidance literature:: aluminium trichloride; aluminium chloride; In dichloromethane;

Reference yield:

: 771-99-3
4-phenylpiperidine

: 149353-84-4
4-(4-carboxyphenyl)-piperidine-hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridine / tetrahydrofuran / 14 h / 0 - 25 °C / Inert atmosphere

2.1: aluminum (III) chloride / dichloromethane / 0.17 h / 0 °C

2.2: 14.5 h / 25 °C / Inert atmosphere

3.1: hydrogenchloride / water / 18 h / 140 °C / Inert atmosphere

With pyridine; hydrogenchloride; aluminum (III) chloride; In tetrahydrofuran; dichloromethane; water;