Dimethyl Tetrahydropyran-4,4-dicarboxylate

Base Information

Chemical Name:Dimethyl Tetrahydropyran-4,4-dicarboxylate
CAS No.:149777-00-4
Molecular Formula:C₉H₁₄O₅
Molecular Weight:202.207
Hs Code.:2932999099
European Community (EC) Number:677-571-3
DSSTox Substance ID:DTXSID90453849
Nikkaji Number:J2.639.417A
Wikidata:Q72506595
Mol file:149777-00-4.mol

Synonyms:149777-00-4;Dimethyl Tetrahydropyran-4,4-dicarboxylate;Dimethyl dihydro-2H-pyran-4,4(3H)-dicarboxylate;Dimethyl Oxane-4,4-dicarboxylate;Tetrahydropyran-4,4-dicarboxylic Acid Dimethyl Ester;Dimethyl tetrahydropyran-4-dicarboxylate;MFCD02093499;4H-Pyran-4,4-dicarboxylic acid, tetrahydro-, dimethyl ester;dimethyl tetrahydro-4H-pyran-4,4-dicarboxylate;DimethylTetrahydropyran-4,4-dicarboxylate;SCHEMBL2031559;DTXSID90453849;OTIZXJJKKRZQJR-UHFFFAOYSA-N;4H-Pyran-4,4-dicarboxylic acid, tetrahydro-, 4,4-dimethyl ester;AMY20459;AKOS009157966;AS-31475;SY004362;CS-0128396;FT-0689524;T1825;4,4-DIMETHYL OXANE-4,4-DICARBOXYLATE;dimethyl tetrahydro-2H-pyran-4,4-dicarboxylate;EN300-142154;Dimethyl tetrahydro-4H-pyrane-4,4-dicarboxylate;A884235;tetrahydro-4H-pyran-4,4-dicarboxylic acid dimethyl ester

Suppliers and Price of Dimethyl Tetrahydropyran-4,4-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Dimethyl tetrahydropyran-4-dicarboxylate
100mg
$ 305.00

TRC
Dimethyltetrahydropyran-4-dicarboxylate
500mg
$ 65.00

TRC
Dimethyltetrahydropyran-4-dicarboxylate
100mg
$ 45.00

TCI Chemical
Dimethyl Tetrahydropyran-4,4-dicarboxylate >98.0%(GC)
5g
$ 117.00

TCI Chemical
Dimethyl Tetrahydropyran-4,4-dicarboxylate >98.0%(GC)
25g
$ 393.00

Crysdot
Dimethyldihydro-2H-pyran-4,4(3H)-dicarboxylate 97%
25g
$ 266.00

Crysdot
Dimethyldihydro-2H-pyran-4,4(3H)-dicarboxylate 97%
5g
$ 76.00

Crysdot
Dimethyldihydro-2H-pyran-4,4(3H)-dicarboxylate 97%
10g
$ 137.00

Chem-Impex
Dimethyltetrahydropyran-4,4-dicarboxylate,≥98%(GC) ≥98%(GC)
5G
$ 121.34

Chem-Impex
Dimethyltetrahydropyran-4,4-dicarboxylate,≥98%(GC) ≥98%(GC)
25G
$ 449.51

Total 38 raw suppliers

Chemical Property of Dimethyl Tetrahydropyran-4,4-dicarboxylate

Chemical Property:

Vapor Pressure:0.043mmHg at 25°C
Refractive Index:1.455
Boiling Point:238.235°C at 760 mmHg
Flash Point:96.744°C
PSA：61.83000
Density:1,18 g/cm3
LogP:0.12920
Storage Temp.:2-8°C
XLogP3:0.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:202.08412354
Heavy Atom Count:14
Complexity:211

Purity/Quality:

97% ^*data from raw suppliers

Dimethyl tetrahydropyran-4-dicarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s): R36/37/38:;
Hazard Codes:R36/37/38:;
Statements: 36/37/38
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1(CCOCC1)C(=O)OC

Technology Process of Dimethyl Tetrahydropyran-4,4-dicarboxylate

There total 1 articles about Dimethyl Tetrahydropyran-4,4-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.5%

: 5414-19-7
1,1'-oxybis(2-bromo-ethane)

: 108-59-8
malonic acid dimethyl ester

: 149777-00-4
4,4-dimethyl dihydro-2H-pyran-4,4(3H)-dicarboxylate

Guidance literature:: With sodium; In ethanol; for 32h; Reflux;

Reference yield: 92.32%

: 149777-00-4
4,4-dimethyl dihydro-2H-pyran-4,4(3H)-dicarboxylate

: 923020-93-3
4-(methoxycarbonyl) dihydro-2H-pyran-4-carboxilic acid

Guidance literature:: With sodium hydroxide; In methanol;

Reference yield:

: 149777-00-4
4,4-dimethyl dihydro-2H-pyran-4,4(3H)-dicarboxylate

: (R)-(3-(4-(2-((2,6-difluorobenzyl)oxy)-1,1,1,3,3,3-hexafluoropropan-2-yl)phenyl)-3-((4-fluorophenyl)sulfonyl)pyrrolidin-1-yl)-(4-(hydroxymethyl)tetrahydro-2H-pyran-4-yl)methanone

Guidance literature:: Multi-step reaction with 4 steps

1: diisobutylaluminium hydride / dichloromethane; toluene / 3 h / -78 °C

2: sodium tetrahydroborate; methanol / methanol / 1 h / 0 °C

3: sodium hydroxide / tetrahydrofuran; methanol / 15 h / 70 °C

4: N-ethyl-N,N-diisopropylamine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / N,N-dimethyl-formamide / 2 h / 70 °C / Sealed tube

With methanol; sodium tetrahydroborate; diisobutylaluminium hydride; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; toluene;