(4-Methoxy-3-nitrophenyl)methanol

Base Information

• Chemical Name: (4-Methoxy-3-nitrophenyl)methanol
• CAS No.: 41870-24-0
• Molecular Formula: CH3OC6H3(NO2)CH2OH
• Molecular Weight: 183.164
• Hs Code.: 2909499000
• DSSTox Substance ID: DTXSID10403240
• Nikkaji Number: J465.139A
• Wikidata: Q82206857
• Mol file: 41870-24-0.mol

Synonyms:(4-methoxy-3-nitrophenyl)methanol;41870-24-0;4-Methoxy-3-nitrobenzyl alcohol;4-METHOXY-3-NITROBENZYL ALCOHOL 97;SCHEMBL1667910;3-Nitro-4-methoxybenzenemethanol;DTXSID10403240;MFCD02683526;AKOS005174733;AKOS015913620;4-Methoxy-3-nitrobenzyl alcohol, 97%;LS-04589;CS-0063190;FT-0769809;EN300-1858157;Z362593482

Chemical Property of (4-Methoxy-3-nitrophenyl)methanol

Chemical Property:

• Vapor Pressure: 4.84E-06mmHg at 25°C
• Melting Point: 68-71 °C(lit.)
• Refractive Index: 1.574
• Boiling Point: 367.3°C at 760 mmHg
• PKA: 13.57±0.10(Predicted)
• Flash Point: 175.9°C
• PSA: 75.28000
• Density: 1.316g/cm³
• LogP: 1.61890
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 183.05315777
• Heavy Atom Count: 13
• Complexity: 180

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-methoxy-3-nitrobenzyl alcohol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C(C=C1)CO)[N+](=O)[O-]

Technology Process of (4-Methoxy-3-nitrophenyl)methanol

There total 12 articles about (4-Methoxy-3-nitrophenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-methoxy-3-nitrobenzaldehyde (31680-08-7) → (4-methoxy-3-nitrophenyl)methanol (41870-24-0)

Guidance literature:

4-methoxy-3-nitrobenzaldehyde; With sodium tetrahydroborate; In tetrahydrofuran; ethanol; at 10 - 20 ℃; for 2.16667h;

With water; at 20 ℃; for 0.5h;

Reference yield: 98.0%

4-methoxy-3-nitrobenzoic acid (89-41-8) → (4-methoxy-3-nitrophenyl)methanol (41870-24-0)

Guidance literature:

Reference yield:

4-Methoxybenzyl alcohol (105-13-5) → (4-methoxy-3-nitrophenyl)methanol (41870-24-0) + 4-methoxy-benzaldehyde (123-11-5)

Guidance literature:

With Nitrogen dioxide; In acetonitrile; at 140 ℃; for 5h; under 760.051 Torr; Sealed tube;

DOI:10.1016/j.catcom.2017.08.003

upstream raw materials:

4-methoxy-3-nitrobenzaldehyde

4-methoxy-3-nitrobenzyl chloride

4-hydroxymethyl-2-nitrophenol

methyl iodide