1-ISOPROPYL-N-METHOXY-N-METHYL-1H-BENZO[D][1,2,3]TRIAZOLE-6-CARBOXAMIDE

Base Information

Chemical Name:1-ISOPROPYL-N-METHOXY-N-METHYL-1H-BENZO[D][1,2,3]TRIAZOLE-6-CARBOXAMIDE
CAS No.:467235-06-9
Molecular Formula:C₁₂H₁₆N₄O₂
Molecular Weight:248.285
Hs Code.:
Mol file:467235-06-9.mol

Synonyms:1-ISOPROPYL-N-METHOXY-N-METHYL-1H-BENZO[D][1,2,3]TRIAZOLE-6-CARBOXAMIDE

Suppliers and Price of 1-ISOPROPYL-N-METHOXY-N-METHYL-1H-BENZO[D][1,2,3]TRIAZOLE-6-CARBOXAMIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-ISOPROPYL-N-METHOXY-N-METHYL-1H-BENZO[D][1,2,3]TRIAZOLE-6-CARBOXAMIDE 95.00%
5MG
$ 499.63

Total 2 raw suppliers

Chemical Property of 1-ISOPROPYL-N-METHOXY-N-METHYL-1H-BENZO[D][1,2,3]TRIAZOLE-6-CARBOXAMIDE

Chemical Property:

PSA：60.25000
LogP:1.64560

Purity/Quality:

98%min ^*data from raw suppliers

1-ISOPROPYL-N-METHOXY-N-METHYL-1H-BENZO[D][1,2,3]TRIAZOLE-6-CARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-ISOPROPYL-N-METHOXY-N-METHYL-1H-BENZO[D][1,2,3]TRIAZOLE-6-CARBOXAMIDE

There total 6 articles about 1-ISOPROPYL-N-METHOXY-N-METHYL-1H-BENZO[D][1,2,3]TRIAZOLE-6-CARBOXAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 467235-05-8
3-isopropyl-3H-benzotriazole-5-carboxylic acid

: 79-37-8
oxalyl dichloride

sodium dihydrogenphosphate, aqueous bicarbonate: sodium dihydrogenphosphate, aqueous bicarbonate

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 108-18-9
diisopropylamine

: 467235-06-9
3-isopropyl-3H-benzotriazole-5-carboxylic acid methoxy methyl amide

Guidance literature:: With hydrogenchloride; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 3-isopropyl-3H-benzotriazole-5-carbonyl chloride

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 467235-06-9
3-isopropyl-3H-benzotriazole-5-carboxylic acid methoxy methyl amide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; at 22 ℃; for 16h;
DOI:10.1021/jm050346q

Reference yield:

: 619-05-6
3,4-diaminobenzoic acid

: 467235-06-9
3-isopropyl-3H-benzotriazole-5-carboxylic acid methoxy methyl amide

Guidance literature:: Multi-step reaction with 4 steps

1.1: tetrahydrofuran; dimethylformamide / 2 h / 22 °C

1.2: 36 percent / NaBH(OAc)3 / dimethylformamide; tetrahydrofuran / 2.5 h

2.1: NaNO₂; aq. HCl / 1 h / 0 °C

3.1: oxalyl chloride; DMF / CH₂Cl₂ / 5 h / 22 °C

4.1: 1.32 g / N,N-diisopropylethylamine / CH₂Cl₂; dimethylformamide / 16 h / 22 °C

With hydrogenchloride; oxalyl dichloride; N-ethyl-N,N-diisopropylamine; N,N-dimethyl-formamide; sodium nitrite; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm050346q