9,10-DIHYDRO-GAMMA-OXO-2-PHENANTHRENE-BUTYRIC ACID)

Base Information

• Chemical Name: 9,10-DIHYDRO-GAMMA-OXO-2-PHENANTHRENE-BUTYRIC ACID)
• CAS No.: 52135-43-0
• Molecular Formula: C₁₈H₁₆O₃
• Molecular Weight: 280.323
• Hs Code.: 2918300090
• Mol file: 52135-43-0.mol

Synonyms:9,10-DIHYDRO-GAMMA-OXO-2-PHENANTHRENE-BUTYRIC ACID)

Chemical Property of 9,10-DIHYDRO-GAMMA-OXO-2-PHENANTHRENE-BUTYRIC ACID)

Chemical Property:

• Melting Point: 153-157 °C
• Boiling Point: 530.6±43.0 °C(Predicted)
• PKA: 4.55±0.17(Predicted)
• PSA: 54.37000
• Density: 1.244±0.06 g/cm3(Predicted)
• LogP: 3.49970
• Solubility.: Chloroform, DCM, Methanol

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 9,10-Dihydro-γ-oxo-2-phenanthrenebutanoic Acid is an intermediate in synthesizing Benz[l]aceanthrylene (B183405), which is a mutagenic agent.

Technology Process of 9,10-DIHYDRO-GAMMA-OXO-2-PHENANTHRENE-BUTYRIC ACID)

There total 4 articles about 9,10-DIHYDRO-GAMMA-OXO-2-PHENANTHRENE-BUTYRIC ACID) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

succinic acid anhydride (108-30-5) + 9,10-dihydrophenanthrene (776-35-2) → 4-(9,10-dihydro-[2]phenanthryl)-4-oxo-butyric acid (52135-43-0)

Guidance literature:

With aluminium trichloride; nitrobenzene;

DOI:10.1021/ja01286a042

Reference yield:

diethyl malonate (105-53-3) → 4-(9,10-dihydro-[2]phenanthryl)-4-oxo-butyric acid (52135-43-0)

Guidance literature:

With sodium; benzene; Behandeln des Reaktionsprodukts mit aethanol. Kalilauge und Erhitzen der danach isolierten Dicarbonsaeure auf 160grad;

DOI:10.1021/ja01286a042

Reference yield:

succinic acid anhydride (108-30-5) + aluminium trichloride (7446-70-0) + 9,10-dihydrophenanthrene (776-35-2) + nitrobenzene (98-95-3,26969-40-4) → 4-(9,10-dihydro-[2]phenanthryl)-4-oxo-butyric acid (52135-43-0)

Guidance literature:

DOI:10.1021/ja01286a042

upstream raw materials:

succinic acid anhydride

9,10-dihydrophenanthrene

aluminium trichloride

nitrobenzene

Downstream raw materials:

9,10-Dihydro-2-phenanthrenebutanoic Acid