N-methylthiophene-3-carboxamide

Base Information

Chemical Name:N-methylthiophene-3-carboxamide
CAS No.:59906-38-6
Molecular Formula:C6H7NOS
Molecular Weight:141.19
Hs Code.:
DSSTox Substance ID:DTXSID00878908
Nikkaji Number:J1.622.494D
Wikidata:Q82860926
Mol file:59906-38-6.mol

Synonyms:N-methylthiophene-3-carboxamide;59906-38-6;N-methyl-3-thiophenecarboxamide;SCHEMBL3415908;3-Thiophencarboxamide,N-methyl-;DTXSID00878908;GIKWERIUUJADFI-UHFFFAOYSA-N;AKOS008982333;AK-830/25033018

Suppliers and Price of N-methylthiophene-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-METHYL-3-THIOPHENECARBOXAMIDE 95.00%
5MG
$ 500.21

Total 1 raw suppliers

Chemical Property of N-methylthiophene-3-carboxamide

Chemical Property:

PSA：57.34000
LogP:1.49860
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:141.02483502
Heavy Atom Count:9
Complexity:116

Purity/Quality:: N-METHYL-3-THIOPHENECARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC(=O)C1=CSC=C1

Technology Process of N-methylthiophene-3-carboxamide

There total 4 articles about N-methylthiophene-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 872-31-1
3-Bromothiophene

: 14040-11-0
tungsten hexacarbonyl

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 357405-56-2
thiophene-3-(N-methoxy-N-methyl)carboxamide

: 59906-38-6
N-methylthiophene-3-carboxamide

Guidance literature:: With dmap; potassium phosphate; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 120 ℃; for 0.333333h; Microwave irradiation;
DOI:10.1021/jo102151u

Reference yield:

: 41507-35-1
3-thiophene carboxylic acid chloride

: 74-89-5
methylamine

: 59906-38-6
N-methylthiophene-3-carboxamide

Guidance literature:: In diethyl ether; water; at 0 - 20 ℃;
DOI:10.1021/ol203251s

Reference yield:

: 88-13-1
3-Thiophene carboxylic acid

: 74-89-5
methylamine

: 59906-38-6
N-methylthiophene-3-carboxamide

Guidance literature:: 3-Thiophene carboxylic acid; With 1,1'-carbonyldiimidazole; In dichloromethane; at 20 ℃; for 0.333333h; Inert atmosphere;

methylamine; In dichloromethane; water; at 20 ℃; for 3h; Inert atmosphere;
DOI:10.1021/acs.joc.9b01699