ETHYL CIS-4-PHENYL-2-BUTENOATE

Base Information

• Chemical Name: ETHYL CIS-4-PHENYL-2-BUTENOATE
• CAS No.: 559062-83-8
• Molecular Formula: C12H14O2
• Molecular Weight: 190.242
• Mol file: 559062-83-8.mol

Synonyms:ETHYL CIS-4-PHENYL-2-BUTENOATE

Chemical Property of ETHYL CIS-4-PHENYL-2-BUTENOATE

Chemical Property:

• PSA: 26.30000
• LogP: 2.34840

Purity/Quality:

95% ^*data from raw suppliers

Ethylcis-4-phenyl-2-butenoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL CIS-4-PHENYL-2-BUTENOATE

There total 12 articles about ETHYL CIS-4-PHENYL-2-BUTENOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

benzyl bromide (100-39-0) + (Z)-ethyl 3-(tributylstannyl)propenoate (82101-76-6,106335-84-6,128266-87-5) → ethyl (2Z)-4-phenyl-2-butenoate (559062-83-8)

Guidance literature:

Pd(PPh₃)2(N-phtalimidate)Br; In toluene; at 60 ℃; for 18h;

DOI:10.1016/j.tet.2005.06.080

Reference yield: 90.0%

C19H15O4Si(1-)*C6H15N*H(1+) + ethyl (Z)-3-bromopropenoate (31930-34-4) → ethyl (2Z)-4-phenyl-2-butenoate (559062-83-8)

Guidance literature:

With tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; (1,2-dimethoxyethane)dichloronickel(II); 4,4'-di-tert-butyl-2,2'-bipyridine; In N,N-dimethyl-formamide; at 27 ℃; for 24h; Sealed tube; Inert atmosphere; Irradiation;

DOI:10.1021/acs.orglett.6b00024

Reference yield: 89.0%

phenylacetaldehyde (122-78-1) + ethyl (triphenylphosphoranylidene)acetate (1099-45-2) → ethyl 3-benzylacrylate (54966-42-6,1466-22-4) + ethyl (2Z)-4-phenyl-2-butenoate (559062-83-8)

Guidance literature:

In benzene; at 20 ℃;

DOI:10.1021/jo972106r

upstream raw materials:

phenylacetaldehyde

ethyl (triphenylphosphoranylidene)acetate

diazoacetic acid ethyl ester

(carbethoxymethyl)triphenylphosphonium bromide

Downstream raw materials:

(R,R)-3-(phenylmethyl)oxiranemethanol

(2S-trans)-3-(Phenylmethyl)oxiranemethanol

cis-1-bromo-4-phenyl-2-butene

(Z)-4-phenylbut-2-en-1-ol