N,2,5-trimethylbenzamide

Base Information

Chemical Name:N,2,5-trimethylbenzamide
CAS No.:60034-93-7
Molecular Formula:C10H13NO
Molecular Weight:163.21632
Hs Code.:2924299090
DSSTox Substance ID:DTXSID20358939
Wikidata:Q82139874
Mol file:60034-93-7.mol

Synonyms:N,2,5-trimethylbenzamide;60034-93-7;SCHEMBL4766299;DTXSID20358939;Benzamide,N,2,5-trimethyl-(9ci);AKOS008933411;Z32016577

Suppliers and Price of N,2,5-trimethylbenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N,2,5-trimethylbenzamide

Chemical Property:

PSA：32.59000
LogP:2.23780
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:163.099714038
Heavy Atom Count:12
Complexity:167

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)C)C(=O)NC

Technology Process of N,2,5-trimethylbenzamide

There total 5 articles about N,2,5-trimethylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 74-89-5
methylamine

: 610-72-0
2,5-dimethylbenzoic acid

: 60034-93-7
2,5-dimethyl-N-methylbenzamide

Guidance literature:

Reference yield: 69.0%

: 74786-81-5
m-methyl-N-methylbenzamide

: 75-16-1
methylmagnesium bromide

: 60034-93-7
2,5-dimethyl-N-methylbenzamide

: N,2,3,6-tetramethylbenzamide

Guidance literature:: With lithium manganese chloride; 1-Bromo-2-chloroethane; In tetrahydrofuran; at 25 ℃; for 24h; Schlenk technique;
DOI:10.1021/acs.orglett.7b02778

Reference yield:

: 610-72-0
2,5-dimethylbenzoic acid

: 60034-93-7
2,5-dimethyl-N-methylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride; triethylamine / tetrahydrofuran / 0.33 h / 20 °C

2: 2.9 g / tetrahydrofuran / 2 h

With thionyl chloride; triethylamine; In tetrahydrofuran;
DOI:10.1016/j.bmc.2005.01.056