L-lactate

Base Information

• Chemical Name: L-lactate
• CAS No.: 72-08-2
• Molecular Formula: C₃H₅O₃
• Molecular Weight: 89.0709
• European Community (EC) Number: 248-692-5
• UNII: 435SSH7H89
• DSSTox Substance ID: DTXSID801018949
• Nikkaji Number: J555.329F
• Wikidata: Q27102013
• Mol file: 72-08-2.mol

Synonyms:L-lactate;L-Lactate ion;(2S)-2-hydroxypropanoate;Lactate ion, L-;Lactate, (S)-;(S)-lactate;(S)-(+)-Lactate ion;L(+)-lactate;Lactic acid, ION(1-), L-;435SSH7H89;72-08-2;UNII-435SSH7H89;Propanoic acid, 2-hydroxy-, ION(1-), (2S)-;(+)-Lactate;CHEMBL507018;L-(+)-Lactate;27848-80-2;Lithium L(+)-lactate;Lithium;2o9a;(2S)-2-oxidanylpropanoate;CHEBI:16651;JVTAAEKCZFNVCJ-REOHCLBHSA-M;DTXSID801018949;BDBM50257205;AKOS040752623;A839653;A876858;Q27102013;148182-33-6

Chemical Property of L-lactate

Chemical Property:

• PSA: 60.36000
• LogP: -1.88290
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 89.023869017
• Heavy Atom Count: 6
• Complexity: 53.5

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)[O-])O
• Isomeric SMILES: C[C@@H](C(=O)[O-])O

Technology Process of L-lactate

There total 5 articles about L-lactate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

D-glucose (50-99-7) → D-lactate anion (72-08-2,113-21-3,311-80-8,1927-28-2,15552-92-8,38140-75-9) + glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0)

Guidance literature:

With potassium dihydrogenphosphate; oxygen; magnesium sulfate; In water; at 30 ℃; for 77h; pH=Ca. 3.0; Reagent/catalyst; Time; Microbiological reaction;

Reference yield: 63.0%

C8H17O6P + cyclohexylamine (108-91-8,157973-60-9) → C3H7O6P*3C6H13N + D-lactate anion (72-08-2,113-21-3,311-80-8,1927-28-2,15552-92-8,38140-75-9)

Guidance literature:

C₈H₁₇O₆P; With trimethylsilyl bromide; In dichloromethane; Inert atmosphere;

With potassium hydroxide; In water;

cyclohexylamine; In water;

DOI:10.1039/b909241b

Reference yield:

(S)-D-lactoylglutathione (41656-56-8) → GLUTATHIONE (70-18-8) + D-lactate anion (72-08-2,113-21-3,311-80-8,1927-28-2,15552-92-8,38140-75-9)

Guidance literature:

With Zn inactive glyoxalase I (Glo₁) enzyme from Pseudomonas aeruginosa; Kinetics; Enzymatic reaction;

DOI:10.1002/chem.201405402

upstream raw materials:

D-glucose

cyclohexylamine

C₂₀H₃₈N₆O₇S

(S)-D-lactoylglutathione

Downstream raw materials:

propylene glycol

Refernces

• 1、 -. "Fermentation process using yeast cells having disrupted pathway from dihydroxyacetone phosphate to glycerol". Paragraph 0127; 0128; 0129; 0130. . Retrieved 2013/05/09.
• 2、 Walker, Scott R.,Cumming, Hemi,Parker, Emily J.. "Substrate and reaction intermediate mimics as inhibitors of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase". supporting information; experimental part. p. 3031 - 3035. Retrieved 2011/02/25.