1-FORMYL-2-METHOXYPYRROLIDINE

Base Information

• Chemical Name: 1-FORMYL-2-METHOXYPYRROLIDINE
• CAS No.: 61020-06-2
• Molecular Formula: C6H11NO2
• Molecular Weight: 129.16
• Hs Code.: 2933990090
• Mol file: 61020-06-2.mol

Synonyms:1-FORMYL-2-METHOXYPYRROLIDINE;1-Pyrrolidinecarboxaldehyde, 2-methoxy- (9CI);2-methoxy-1-pyrrolidinecarboxaldehyde

Chemical Property of 1-FORMYL-2-METHOXYPYRROLIDINE

Chemical Property:

• Vapor Pressure: 0.085mmHg at 25°C
• Refractive Index: 1.474
• Boiling Point: 225.718°C at 760 mmHg
• PKA: -2.38±0.40(Predicted)
• Flash Point: 103.889°C
• PSA: 29.54000
• Density: 1.076g/cm³
• LogP: 0.78490

Purity/Quality:

97% ^*data from raw suppliers

1-FORMYL-2-METHOXYPYRROLIDINE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-FORMYL-2-METHOXYPYRROLIDINE

There total 3 articles about 1-FORMYL-2-METHOXYPYRROLIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1-pyrrolidinecarboxaldehyde (3760-54-1) + methanol (67-56-1) → 2-methoxy-1-pyrrolidinecarboxaldehyde (61020-06-2)

Guidance literature:

With tetrabutylammonium tetrafluoroborate; Electrolysis; Sonication;

DOI:10.1055/s-0037-1611774

Reference yield:

1-pyrrolidinecarboxaldehyde (3760-54-1) + methanol (67-56-1) → 2-methoxy-1-pyrrolidinecarboxaldehyde (61020-06-2) + 2,5-dimethoxypyrrolidine-1-carbaldehyde + 2,5-dimethoxypyrrolidine-1-carbaldehyde

Guidance literature:

With tetrabutylammonium tetrafluoroborate; Sonication; Electrolysis;

DOI:10.1055/s-0037-1611774

Reference yield:

→ 2-methoxy-1-pyrrolidinecarboxaldehyde (61020-06-2)

Guidance literature:

1-Formyl-pyrrolidin, CH3OH, anodische Alkoxylierung, Tab. 2;

upstream raw materials:

1-pyrrolidinecarboxaldehyde

methanol

Downstream raw materials:

N-formyl-2-(2,4,6-trimethylphenyl)-pyrrolidine

N-formyl-2-phenylpyrrolidine

2-<2-(3,4-dimethoxyphenyl)-2-oxoethyl>1-pyrrolidinecarboxaldehyde

(E)-2-<2-(3,4-dimethoxyphenyl)ethenyl>-1-pyrrolidinecarboxaldehyde

Refernces

• 1、 Amri, Nasser,Guthrie, Duncan,Skilton, Ryan A.,Wirth, Thomas. "Efficient Flow Electrochemical Alkoxylation of Pyrrolidine-1-carbaldehyde". . p. 1183 - 1186. Retrieved 2019.