6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepine

Base Information

Chemical Name:6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepine
CAS No.:5768-55-8
Molecular Formula:C8H12N2
Molecular Weight:136.197
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50437403
Nikkaji Number:J603.918I
Wikidata:Q82252893
Mol file:5768-55-8.mol

Synonyms:6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepine;5768-55-8;1,2-pentamethyleneimidazole;5H-Imidazo[1,2-a]azepine,6,7,8,9-tetrahydro-;SCHEMBL173406;DTXSID50437403;MBVCARRYXQUTLF-UHFFFAOYSA-N;MFCD11870772;AKOS015907673;SY310363;CS-0143362;FT-0646349;A831557

Suppliers and Price of 6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepine 97%
1g
$ 488.00

Crysdot
6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepine 95+%
1g
$ 459.00

Atlantic Research Chemicals
6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepine 95%
1gm:
$ 420.61

American Custom Chemicals Corporation
6,7,8,9-TETRAHYDRO-5H-IMIDAZO[1,2-A]AZEPINE 95.00%
5G
$ 909.56

Alichem
6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepine
1g
$ 468.64

AK Scientific
6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepine
1g
$ 708.00

Total 9 raw suppliers

Chemical Property of 6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepine

Chemical Property:

Vapor Pressure:0.002mmHg at 25°C
Refractive Index:1.607
Boiling Point:297.222 °C at 760 mmHg
Flash Point:133.555 °C
PSA：17.82000
Density:1.139 g/cm³
LogP:1.60950
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:136.100048391
Heavy Atom Count:10
Complexity:114

Purity/Quality:

98%Min ^*data from raw suppliers

6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC2=NC=CN2CC1

Technology Process of 6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepine

There total 6 articles about 6,7,8,9-Tetrahydro-5H-imidazo[1,2-a]azepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.9%

: 105-60-2,9012-16-2
caprolactam

: 645-36-3
2,2-diethoxy-ethanamine

: 5768-55-8
2,3,4,6,7,8,9,10-octahydropyrimido<1,2-a>azepino

Guidance literature:: tin(IV) chloride; In dichloromethane; 1,3,5-trimethyl-benzene; for 45h; Heating;
DOI:10.1021/jo00096a066

Reference yield: 63.0%

: 191542-42-4
1-<5-(phenylselanyl)pentyl>-2-tosyl-1H-imidazole

: 5768-55-8
2,3,4,6,7,8,9,10-octahydropyrimido<1,2-a>azepino

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; for 5h; Heating;
DOI:10.1016/S0040-4039(97)00740-5

Reference yield:

: 60274-60-4
1-chloro-5-iodopentane

: 5768-55-8
2,3,4,6,7,8,9,10-octahydropyrimido<1,2-a>azepino

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) sodium borohydride / 1) ethanol, 0 deg C, 30 min; 2) ethanol, rt, 16 h

2: 64 percent / sodium iodide / acetone / 18 h / Heating

3: 1.) NaH / 1) acetonitrile, reflux, 1 h; 2) acetonitrile, reflux, 2 h

4: 63 percent / Bu₃SnH, AIBN / toluene / 10 h / Heating

With sodium tetrahydroborate; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; sodium hydride; sodium iodide; In acetone; toluene;
DOI:10.1016/S0040-4020(99)00104-0