1-(Difluoro(trimethylsilyl)methyl)-2-phenyl-1H-imidazole

Base Information

Chemical Name:1-(Difluoro(trimethylsilyl)methyl)-2-phenyl-1H-imidazole
CAS No.:341529-08-6
Molecular Formula:C13H16 F2 N2 Si
Molecular Weight:266.36200
Hs Code.:2933290090
DSSTox Substance ID:DTXSID10458816
Wikidata:Q82282349
Mol file:341529-08-6.mol

Synonyms:341529-08-6;1-(Difluoro(trimethylsilyl)methyl)-2-phenyl-1H-imidazole;1-[difluoro(trimethylsilyl)methyl]-2-phenyl-1H-imidazole;2-Phenyl-imidazol-1-yl-difluoromethyl trimethylsilane;DTXSID10458816;HZGODXYTPTURKN-UHFFFAOYSA-N;1H-IMIDAZOLE,1-[DIFLUORO(TRIMETHYLSILYL)METHYL]-2-PHENYL-

Suppliers and Price of 1-(Difluoro(trimethylsilyl)methyl)-2-phenyl-1H-imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(Difluoro(trimethylsilyl)methyl)-2-phenyl-1H-imidazole 95+%
1g
$ 366.00

Chemenu
1-(Difluoro(trimethylsilyl)methyl)-2-phenyl-1H-imidazole 95%
1g
$ 346.00

Total 3 raw suppliers

Chemical Property of 1-(Difluoro(trimethylsilyl)methyl)-2-phenyl-1H-imidazole

Chemical Property:

Vapor Pressure:0.00029mmHg at 25°C
PSA：17.82000
LogP:4.28830
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:266.10508138
Heavy Atom Count:18
Complexity:285

Purity/Quality:

99% ^*data from raw suppliers

1-(Difluoro(trimethylsilyl)methyl)-2-phenyl-1H-imidazole 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[Si](C)(C)C(N1C=CN=C1C2=CC=CC=C2)(F)F

Technology Process of 1-(Difluoro(trimethylsilyl)methyl)-2-phenyl-1H-imidazole

There total 2 articles about 1-(Difluoro(trimethylsilyl)methyl)-2-phenyl-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 75-77-4
chloro-trimethyl-silane

: 341529-06-4
1-Bromodifluoromethyl-2-phenylimidazole

: 341529-08-6
2-Phenylimidazole-1-yldifluromethyltrimethylsilane

Guidance literature:: With P(NEt)3; In dichloromethane; at -70 ℃; for 1h;
DOI:10.1055/s-2001-11389

Reference yield:

: 670-96-2
2-Phenylimidazole

: 341529-08-6
2-Phenylimidazole-1-yldifluromethyltrimethylsilane

Guidance literature:: Multi-step reaction with 2 steps

1.1: tBuOK / tetrahydrofuran

1.2: dimethylformamide / 20 °C

2.1: 75 percent / P(NEt)3 / CH₂Cl₂ / 1 h / -70 °C

With P(NEt)3; potassium tert-butylate; In tetrahydrofuran; dichloromethane;
DOI:10.1055/s-2001-11389