1-(2,4-DINITROPHENYL)-PIPERAZINE HCL

Base Information

• Chemical Name: 1-(2,4-DINITROPHENYL)-PIPERAZINE HCL
• CAS No.: 31284-04-5
• Molecular Formula: C10H12 N4 O4
• Molecular Weight: 252.23
• Hs Code.: 2933599090
• Mol file: 31284-04-5.mol

Synonyms:1-(2,4-Dinitrophenyl)piperazine

Chemical Property of 1-(2,4-DINITROPHENYL)-PIPERAZINE HCL

Chemical Property:

• PSA: 106.91000
• LogP: 3.15480

Purity/Quality:

NLT 98% ^*data from raw suppliers

1-(2,4-Dinitrophenyl)piperazineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2,4-DINITROPHENYL)-PIPERAZINE HCL

There total 17 articles about 1-(2,4-DINITROPHENYL)-PIPERAZINE HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

piperazine (110-85-0) + 2,4-dinitrophenyl benzenesulfonate (970-88-7) → 2,4-Dinitrophenol (51-28-5) + 1-(phenylsulphonyl)piperazine (14172-55-5) + N-(2,4-dinitrophenyl)piperidine (31284-04-5) + benzenesulfonic acid (98-11-3)

Guidance literature:

With hydrogenchloride; In water; dimethyl sulfoxide; at 25 ℃; Further Variations:; Reaction partners; Kinetics;

DOI:10.1021/jo049812u

Reference yield:

piperazine (110-85-0) + 2,4-dinitrophenyl 4-methylbenzenesulfonate (742-25-6) → 2,4-Dinitrophenol (51-28-5) + 1-tosylpiperazine (27106-51-0) + toluene-4-sulfonic acid (104-15-4) + N-(2,4-dinitrophenyl)piperidine (31284-04-5)

Guidance literature:

With hydrogenchloride; In water; dimethyl sulfoxide; at 25 ℃; Kinetics;

DOI:10.1021/jo049812u

Reference yield:

piperazine (110-85-0) + 2,4-dinitrophenyl 4-chlorobenzenesulfonate (973-63-7) → 2,4-Dinitrophenol (51-28-5) + 4-chloro-benzenesulfonic acid (98-66-8) + N-(2,4-dinitrophenyl)piperidine (31284-04-5) + 1‐(4‐chlorophenylsulfonyl)piperazine (16017-53-1)

Guidance literature:

With hydrogenchloride; In water; dimethyl sulfoxide; at 25 ℃; Kinetics;

DOI:10.1021/jo049812u

upstream raw materials:

piperazine

2,3-<3-norcaren-endo-2,5-diyl>-N-(2',4'-dinitrophenoxy)succinimide

2,4-Dinitrofluorobenzene

1-chloro-2,4-dinitro-benzene

Refernces

• 1、 Um, Ik-Hwan,Kim, Min-Young,Kang, Tae-Ah,Dust, Julian M.. "Kinetic study on SNAr reaction of 1-(Y-Substituted-phenoxy)-2,4- dinitrobenzenes with cyclic secondary amines in acetonitrile: Evidence for cyclic transition-state structure". supporting information. p. 7025 - 7031. Retrieved 2014/08/18.
• 2、 Um, Ik-Hwan,Im, Li-Ra,Kang, Ji-Sun,Bursey, Samantha S.,Dust, Julian M.. "Mechanistic assessment of SNAr displacement of halides from 1-Halo-2,4-dinitrobenzenes by selected primary and secondary amines: Br?nsted and Mayr analyses". supporting information. p. 9738 - 9746. Retrieved 2013/01/15.