3-(Methylamino)propan-1-ol

Base Information

• Chemical Name: 3-(Methylamino)propan-1-ol
• CAS No.: 42055-15-2
• Molecular Formula: C4H11 N O
• Molecular Weight: 89.1374
• Hs Code.: 2922199090
• European Community (EC) Number: 677-457-3
• UNII: 7D9DNX69QV
• DSSTox Substance ID: DTXSID50436133
• Nikkaji Number: J89.438I
• Wikidata: Q72487343
• Mol file: 42055-15-2.mol

Synonyms:3-(Methylamino)propan-1-ol;42055-15-2;3-(Methylamino)-1-propanol;3-Methylamino-1-propanol;methylpropanolamine;(3-hydroxypropyl)methylamine;n-methylpropanolamine;AMP-p 5;7D9DNX69QV;1-Propanol, 3-(methylamino)-;3-methylaminopropanol;3-methylamino-propanol;3-(methylamino)propanol;UNII-7D9DNX69QV;3-methylamino-propan-1-ol;gamma-(Methylamino)propanol;n-methyl-3-hydroxypropylamine;N-(3-hydroxypropyl)methylamine;DTXSID50436133;3-Methylamino-1-propanol, 96%;KRGXWTOLFOPIKV-UHFFFAOYSA-N;N-(3-hydroxypropyl)-N-methylamine;STR10027;MFCD06797456;.GAMMA.-(METHYLAMINO)PROPANOL;AKOS002682745;CS-W007469;SB83777;M1484;EN300-141645;A851613;Z104756980

Chemical Property of 3-(Methylamino)propan-1-ol

Chemical Property:

• Vapor Pressure: 0.679mmHg at 25°C
• Refractive Index: 1.448
• Boiling Point: 169oC
• PKA: 15.06±0.10(Predicted)
• Flash Point: 82oC
• PSA: 32.26000
• Density: 0.917
• LogP: -0.02090
• Storage Temp.: 2-8°C
• Water Solubility.: Slightly soluble in water.
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 89.084063974
• Heavy Atom Count: 6
• Complexity: 23.5

Purity/Quality:

98% ^*data from raw suppliers

3-Methylamino-1-propanol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 10-34-22
• Safety Statements: 16-36/37/39-45-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CNCCCO
• Uses: 3-Methylamino-1-propanol is an alkanolamine that is used to redisperse compacted solids (such as antiperspirant materials) in order to analyze its components.

Technology Process of 3-(Methylamino)propan-1-ol

There total 24 articles about 3-(Methylamino)propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butyl (3-hydroxypropyl)methylcarbamate (98642-44-5) → N-methyl-3-hydroxypropylamine (42055-15-2)

Guidance literature:

With hydrogenchloride; for 17h;

DOI:10.1080/00397919508015894

Reference yield: 86.6%

N-(3-hydroxypropyl)formamide (49807-74-1) → N-methyl-3-hydroxypropylamine (42055-15-2)

Guidance literature:

With potassium hydroxide;

Reference yield: 65.0%

methylamine (74-89-5) + 1-chloro-3-hydroxypropane (627-30-5) → N-methyl-3-hydroxypropylamine (42055-15-2)

Guidance literature:

In ethanol; at 20 ℃; for 144h;

DOI:10.1081/SCC-120021505

upstream raw materials:

trimethylene oxide

methylamine

methyl-carbamic acid-(3-chloro-propyl ester)

allyl alcohol

Downstream raw materials:

2--3-methyl-2H-1,3,2-oxazaphosphorinan-1-oxid

3-methyl-2-(4-chlorophenyl)tetrahydro-1,3-oxazine

1-benzoyloxy-6-(1,3-dioxan-2-yl)-2-[[N-(3-hydroxyprop-1-yl)-N-methylamino]carbonyl]-4-iodobenzene

tert-butyl (3-hydroxypropyl)methylcarbamate

Refernces

• 1、 -. "COMPOUNDS AND METHODS FOR TRANS-MEMBRANE DELIVERY OF MOLECULES". Paragraph 00175. . Retrieved 2019/07/17.
• 2、 Chen, Aimin,Wang, Houyong,Liu, Rui,Bo, Yingying,Hu, Jun. "N-Alkylation of Alkylolamines with Alcohols Over Mesoporous Solid Acid–Base Cs–B–Zr Catalyst". . p. 1182 - 1193. Retrieved 2016/07/06.