4-(5-(3-Hydroxypropyl)-7-methoxybenzofuran-2-yl)-2-methoxyphenol

Base Information

• Chemical Name: 4-(5-(3-Hydroxypropyl)-7-methoxybenzofuran-2-yl)-2-methoxyphenol
• CAS No.: 144735-57-9
• Molecular Formula: C19H20 O5
• Molecular Weight: 328.365
• Hs Code.: 2932999099
• DSSTox Substance ID: DTXSID90425107
• Nikkaji Number: J3.617.517F
• Wikidata: Q72484896
• Mol file: 144735-57-9.mol

Synonyms:144735-57-9;4-(5-(3-Hydroxypropyl)-7-methoxybenzofuran-2-yl)-2-methoxyphenol;4-[5-(3-hydroxypropyl)-7-methoxy-1-benzofuran-2-yl]-2-methoxyphenol;2-4-Hydroxy-3-methoxyphenyl-7-methoxy-5-benzofuranpropanol;ICCB1_000073;SCHEMBL18223919;DTXSID90425107;FEONDVSBLGLFAZ-UHFFFAOYSA-N;2-(4-Hydroxy-3-methoxyphenyl) -7-methoxy-5-benzofuranpropanol;AKOS015999054;J3.617.517F;3-[2-(3-Methoxy-4-hydroxyphenyl)-7-methoxybenzofuran-5-yl]-1-propanol;4-[5-(3-Hydroxypropyl)-7-methoxy-1-benzo[b]furan-2-yl]-2-methoxyphenol

Chemical Property of 4-(5-(3-Hydroxypropyl)-7-methoxybenzofuran-2-yl)-2-methoxyphenol

Chemical Property:

• PSA: 72.06000
• LogP: 3.74750
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 328.13107373
• Heavy Atom Count: 24
• Complexity: 390

Purity/Quality:

99% ^*data from raw suppliers

2-4-Hydroxy-3-methoxyphenyl-7-methoxy-5-benzofuranpropanol ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC(=CC2=C1OC(=C2)C3=CC(=C(C=C3)O)OC)CCCO

Technology Process of 4-(5-(3-Hydroxypropyl)-7-methoxybenzofuran-2-yl)-2-methoxyphenol

There total 21 articles about 4-(5-(3-Hydroxypropyl)-7-methoxybenzofuran-2-yl)-2-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-(benzyloxy)phenyl)benzofuran (135040-86-7) → 2-(4-hydroxy-3-methoxyphenyl)-5-(3-hydroxypropyl)-7-methoxybenzofurane (144735-57-9)

Guidance literature:

With boron tribromide; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.5012/bkcs.2010.31.04.965

Reference yield: 86.1%

3-(2-(4-(tert-butyldimethylsiloxy)-3-methoxyphenyl)-7-methoxybenzofuran-5-yl)propane-1-ol → 2-(4-hydroxy-3-methoxyphenyl)-5-(3-hydroxypropyl)-7-methoxybenzofurane (144735-57-9)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; for 0.5h;

Reference yield: 82.0%

5-((2-methoxycarbonyl)ethyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran (144735-56-8) → 2-(4-hydroxy-3-methoxyphenyl)-5-(3-hydroxypropyl)-7-methoxybenzofurane (144735-57-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 4h; Ambient temperature;

DOI:10.1021/jo00052a046

upstream raw materials:

5-((2-methoxycarbonyl)ethyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran

4-benzyloxy-3-methoxyacetophenone

vanillin

5-bromo-4-hydroxy-3-methoxybenzaldehyde

Downstream raw materials:

4-acetyl-5-(3-acetoxypropyl)-7-methoxy-2-(3'-methoxy-4'-acetoxyphenyl)benzofuran

5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran-4-carbaldehyde

5-(3-hydroxypropyl)-7-methoxy-3-methyl-2-(3'-methoxy-4'-hydroxyphenyl)benzofuran

5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)-3-benzo[b]furan-carbaldehyde

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 144735-57-9 2-(4-Hydroxy-3-methoxyphenyl) -7-methoxy-5-benzofuranpropal

Send

Send

Metric Ton KG G Pound L ML

Send

Send