3-(2-Dimethylaminoethoxy)-bromobenzene

Base Information

• Chemical Name: 3-(2-Dimethylaminoethoxy)-bromobenzene
• CAS No.: 221915-84-0
• Molecular Formula: C10H14BrNO
• Molecular Weight: 244.131
• Hs Code.: 2922299090
• Mol file: 221915-84-0.mol

Synonyms:3-(2-DIMETHYLAMINOETHOXY)-BROMOBENZENE;[2-(3-BROMO-PHENOXY)-ETHYL]-DIMETHYL-AMINE;UKRORGSYN-BB BBV-070799;2-(3-BroMophenoxy)-N,N-diMethylethanaMine

Chemical Property of 3-(2-Dimethylaminoethoxy)-bromobenzene

Chemical Property:

• Boiling Point: 280 °C at 760 mmHg
• Flash Point: 123.1 °C
• PSA: 12.47000
• Density: 1.309 g/cm³
• LogP: 2.38950
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

2-(3-Bromophenoxy)-N,N-dimethylethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(2-Dimethylaminoethoxy)-bromobenzene

There total 5 articles about 3-(2-Dimethylaminoethoxy)-bromobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

3-Bromophenol (591-20-8) + 2-(dimethylamino)ethyl chloride (107-99-3) → [2-(3-bromo-phenoxy)ethyl]-dimethyl-arnine (221915-84-0) + [2-(4-bromophenoxy)ethyl]dimethylamine (2474-07-9)

Guidance literature:

Reference yield: 72.0%

3-Bromophenol (591-20-8) + (2-chloroethyl)dimethylamine hydrochloride (4584-46-7) → [2-(3-bromo-phenoxy)ethyl]-dimethyl-arnine (221915-84-0)

Guidance literature:

With potassium carbonate; potassium iodide; In acetonitrile; at 90 - 115 ℃;

DOI:10.1021/jm2011172

Reference yield: 63.0%

2-(N,N-dimethylamino)ethanol (108-01-0) + 3-Bromophenol (591-20-8) → [2-(3-bromo-phenoxy)ethyl]-dimethyl-arnine (221915-84-0)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 16h;

upstream raw materials:

3-Bromophenol

2-(dimethylamino)ethyl chloride

(2-chloroethyl)dimethylamine hydrochloride

2-(N,N-dimethylamino)ethanol

Downstream raw materials:

[4-[2-(N,N-dimethylamino)ethoxy]phenyl]-2,2,2-trifluoroethanone

[3-[2-(N,N-Dimethylamino)ethoxy]phenyl]-2,2,2-trifluoroethanone

dimethyl-{2-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenoxy]-ethyl}-amine

3-(2-(dimethylamino)ethoxy)phenylboronic acid