1-BENZENESULFONYL-5-BROMO-1H-PYRROLO[2,3-B]PYRIDINE

Base Information Edit

Chemical Name:1-BENZENESULFONYL-5-BROMO-1H-PYRROLO[2,3-B]PYRIDINE
CAS No.:1001070-33-2
Molecular Formula:C13H9 Br N2 O2 S
Molecular Weight:337.197
Hs Code.:2933990090
Mol file:1001070-33-2.mol

Synonyms:5-Bromo-1-(phenylsulfonyl)-1-hydropyrrolo[2,3-b]pyridine

Suppliers and Price of 1-BENZENESULFONYL-5-BROMO-1H-PYRROLO[2,3-B]PYRIDINE

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
1-Benzenesulfonyl-5-bromo-1H-pyrrolo[2,3-b]pyridine AldrichCPR
1 g
$ 637.00

Total 24 raw suppliers

Chemical Property of 1-BENZENESULFONYL-5-BROMO-1H-PYRROLO[2,3-B]PYRIDINE Edit

Chemical Property:

PSA：60.34000
LogP:4.11660

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Benzenesulfonyl-5-bromo-1H-pyrrolo[2,3-b]pyridine AldrichCPR ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,Xn
Statements: 22-36
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-BENZENESULFONYL-5-BROMO-1H-PYRROLO[2,3-B]PYRIDINE

There total 6 articles about 1-BENZENESULFONYL-5-BROMO-1H-PYRROLO[2,3-B]PYRIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 754214-54-5
5-bromo-1-(tert-butyl-dimethyl-silanyl)-1H-pyrrolo[2,3-b]pyridine

: 98-09-9
benzenesulfonyl chloride

: 1001070-33-2
1-(benzenesulfonyl)-5-bromo-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: 5-bromo-1-(tert-butyl-dimethyl-silanyl)-1H-pyrrolo[2,3-b]pyridine; With tetrabutylammomium bromide; sodium hydroxide; In dichloromethane; at 0 ℃; for 0.0833333h;

benzenesulfonyl chloride; In dichloromethane; at 0 - 25 ℃; for 12.25h;

Reference yield: 100.0%

: 98-09-9
benzenesulfonyl chloride

: 183208-35-7
5-bromo-1H-pyrrolo[2,3-b]pyridine

: 1001070-33-2
1-(benzenesulfonyl)-5-bromo-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: 5-bromo-1H-pyrrolo[2,3-b]pyridine; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 0.333333h;

benzenesulfonyl chloride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 2h;

Reference yield:

: 271-63-6
7-Azaindole

: 1001070-33-2
1-(benzenesulfonyl)-5-bromo-1H-pyrrolo[2,3-b]pyridine

Guidance literature:: Multi-step reaction with 5 steps

1.1: triethylamine; formic acid / palladium 10% on activated carbon / 120 h / 0 - 80 °C

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 °C

2.2: 3 h / 0 °C

3.1: bromine; pyridine / dichloromethane / 2 h / 0 °C

4.1: 2,3-dicyano-5,6-dichloro-p-benzoquinone / dichloromethane / 1 h

5.1: sodium hydroxide; tetrabutylammomium bromide / dichloromethane / 0.08 h / 0 °C

5.2: 12.25 h / 0 - 25 °C

With pyridine; formic acid; tetrabutylammomium bromide; bromine; sodium hydride; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium hydroxide; palladium 10% on activated carbon; In dichloromethane; N,N-dimethyl-formamide; mineral oil;