2,5-Diethylfuran

Base Information

• Chemical Name: 2,5-Diethylfuran
• CAS No.: 10504-06-0
• Molecular Formula: C8H12O
• Molecular Weight: 124.183
• UNII: TH825RS1LU
• DSSTox Substance ID: DTXSID70423843
• Nikkaji Number: J1.393.737K
• Wikidata: Q27289965
• Mol file: 10504-06-0.mol

Synonyms:2,5-diethylfuran;10504-06-0;Furan, 2,5-diethyl-;UNII-TH825RS1LU;TH825RS1LU;SCHEMBL45858;DTXSID70423843;OKYQOKFZRFUBJX-UHFFFAOYSA-N;MFCD00129695;AS-20101;Q27289965

Chemical Property of 2,5-Diethylfuran

Chemical Property:

• PSA: 13.14000
• LogP: 2.40440
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 124.088815002
• Heavy Atom Count: 9
• Complexity: 70.6

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,5-Diethylfuran ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=CC=C(O1)CC

Technology Process of 2,5-Diethylfuran

There total 14 articles about 2,5-Diethylfuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

7-oxanorborn-5-ene-2,3-dicarboxylic anhydride (5426-09-5) + ethyl iodide (75-03-6) → 2,5-diethyl-furan (10504-06-0)

Guidance literature:

With nitric acid; at 60 ℃; for 16h; Reagent/catalyst; Temperature;

Reference yield: 84.0%

oct-4-yne-3,6-diol (24434-07-9) → 2,5-diethyl-furan (10504-06-0)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; tributylphosphine; perfluorinated resinsulfonic acid (Nafion-H type); at 130 ℃; for 5h;

DOI:10.1039/c39930000764

Reference yield: 81.0%

2-ethylfuran (3208-16-0) + ethyl iodide (75-03-6) → 2,5-diethyl-furan (10504-06-0)

Guidance literature:

2-ethylfuran; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 0.5h; Inert atmosphere;

ethyl iodide; In tetrahydrofuran; hexane; at 0 - 20 ℃; for 2h; Inert atmosphere;

DOI:10.1039/d0ob00468e

upstream raw materials:

furan

ethene

2-acetyl-5-ethylfuran

2-ethylfuran

Downstream raw materials:

(Z)-1-(3-phenyl-5-ethyl-1,4,2-dioxazol-5-yl)-1-penten-3-one

3,6-Diethyl-phthalonitrile

1,4-diethylbenzene

1-(2-ethyl-4-phenyl-1-tosyl-1H-pyrrol-3-yl)butan-2-one

Refernces

• 1、 Kitamura, Chitoshi,Abe, Yasushi,Kawatsuki, Nobuhiro,Yoneda, Akio,Asada, Kohei,Kobayashi, Takashi,Naito, Hiroyoshi. "Influence of alkyl chain length on the solid-state packing and fluorescence of 1,4,5,8-tetra(alkyl)anthracenes". . p. 119 - 135. Retrieved 2007.
• 2、 Asta, Chimene,Conrad, Juergen,Mika, Sabine,Beifuss, Uwe. "Laccase-catalyzed stereoselective oxidative ring opening of 2,5-dialkylfurans into 2-ene-1,4-diones using air as an oxidant". . p. 3066 - 3069. Retrieved 2011.
• 3、 -. "Beta-LACTAMASE INHIBITOR". Paragraph 0172-0175. . Retrieved 2021/01/11.