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1-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-4-pyrazole boronic acid pinacol ester

Base Information
  • Chemical Name:1-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-4-pyrazole boronic acid pinacol ester
  • CAS No.:1040377-08-9
  • Molecular Formula:C11H19BN2O3
  • Molecular Weight:238.094
  • Hs Code.:2934999090
  • Mol file:1040377-08-9.mol
1-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-4-pyrazole boronic acid pinacol ester

Synonyms:1-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-4-pyrazole boronic acid pinacol ester;1-(2-Hydroxyethyl)-1H-pyrazole-4-boronic acid, pinacol ester;2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]ethan-1-ol, 1-Hydroxy-2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]ethane;2-(4-(4,4,5,5-TetraMethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanol

Suppliers and Price of 1-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-4-pyrazole boronic acid pinacol ester
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-ethanol
  • 2.5g
  • $ 1320.00
  • Synthonix
  • 1-(2-Hydroxyethyl)-1H-pyrazole-4-boronicacidpinacolester 97.0%
  • 25g
  • $ 870.00
  • SynQuest Laboratories
  • 1-(2-Hydroxyethyl)-1H-pyrazole-4-boronic acid, pinacol ester
  • 250 mg
  • $ 175.00
  • SynQuest Laboratories
  • 1-(2-Hydroxyethyl)-1H-pyrazole-4-boronic acid, pinacol ester
  • 1 g
  • $ 575.00
  • Medical Isotopes, Inc.
  • 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-ethanol
  • 250 mg
  • $ 650.00
  • Matrix Scientific
  • 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanol 95+%
  • 1g
  • $ 1143.00
  • Matrix Scientific
  • 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanol 95+%
  • 250mg
  • $ 515.00
  • Crysdot
  • 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanol 95%
  • 10g
  • $ 495.00
  • Crysdot
  • 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethanol 95%
  • 5g
  • $ 292.00
  • ChemScene
  • 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-ethanol ≥97.0%
  • 10g
  • $ 499.00
Total 50 raw suppliers
Chemical Property of 1-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-4-pyrazole boronic acid pinacol ester
Chemical Property:
  • Boiling Point:379.4±22.0 °C(Predicted) 
  • PKA:14.47±0.10(Predicted) 
  • PSA:56.51000 
  • Density:1.13±0.1 g/cm3(Predicted) 
  • LogP:0.17460 
  • Storage Temp.:Inert atmosphere,Store in freezer, under -20°C 
Purity/Quality:

99%, *data from raw suppliers

4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-ethanol *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Uses 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole-1-ethanol, can be used in the synthesis of series of aminopyridines with substituted benzoxazoles, acting c-Met kinase inhibitors.
Technology Process of 1-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-4-pyrazole boronic acid pinacol ester

There total 5 articles about 1-(2-(tetrahydro-2H-pyran-2-yloxy)ethyl)-1H-4-pyrazole boronic acid pinacol ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With sodium hydroxide; In N,N-dimethyl-formamide; at 140 ℃; for 16h;
Guidance literature:
With caesium carbonate; In N,N-dimethyl-formamide; at 70 ℃;
Guidance literature:
With caesium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 18h; Inert atmosphere;
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