((C₆H₃(OCH₃)(CH₂N(CH₃)2))BO)3

Base Information

• Chemical Name: ((C₆H₃(OCH₃)(CH₂N(CH₃)2))BO)3
• CAS No.: 89291-16-7
• Molecular Formula: C₃₀H₄₂B₃N₃O₆
• Molecular Weight: 573.113
• Mol file: 89291-16-7.mol

Synonyms:

Chemical Property of ((C₆H₃(OCH₃)(CH₂N(CH₃)2))BO)3

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of ((C₆H₃(OCH₃)(CH₂N(CH₃)2))BO)3

There total 1 articles about ((C₆H₃(OCH₃)(CH₂N(CH₃)2))BO)3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

Trimethyl borate (121-43-7,63156-11-6) + N,N-dimethyl-4-methoxylbenzylamine (15175-54-9) → ((C6H3(OCH3)(CH2N(CH3)2))BO)3 (89291-16-7)

Guidance literature:

With n-butyllithium; In diethyl ether; hexane; addn. of 1 equiv. BuLi (in hexane) to amine in Et2O, stirring (18 h, room temp.), slow mixing with B(OMe)3 in Et2O (<-60°C, <1 h), slow warming to room temp. (during 24 h); evapn., extn. (CH2Cl2), distn. of extract (reduced pressure), hydrolysis of methylester, azeotropic distn. off of water, recrystn. (toluene or CH2Cl2/petroleum ether); elem. anal.;

DOI:10.1016/S0022-328X(00)99290-8

Reference yield: 75.0%

(S)-1,2-Propanediol (4254-15-3,63625-56-9) + ((C6H3(OCH3)(CH2N(CH3)2))BO)3 (89291-16-7) → 2-(2-[(dimethylamino)methyl]-5-methoxyphenyl)-(4S)-4-methyl-1,3,2-dioxaborolane

Guidance literature:

In toluene; byproducts: H2O; heating equimolar amts. of the boroxine and (S)-1,2-propanediol in toluene;; concn.; distn.; elem. anal.;;

Reference yield: 71.0%

((C6H3(OCH3)(CH2N(CH3)2))BO)3 (89291-16-7) + 2,2-Dimethyl-1,3-propanediol (126-30-7) → 2-(2-[(dimethylamino)methyl]-5-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane (95753-11-0)

Guidance literature:

In toluene; byproducts: H2O; heating equimolar amts. of the boroxine and 2,2-dimethyl-1,3-propanediol in toluene;; concn.; distn.; elem. anal.;;

upstream raw materials:

Trimethyl borate

N,N-dimethyl-4-methoxylbenzylamine

Downstream raw materials:

2-(2-[(dimethylamino)methyl]-5-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborinane