4-Methoxy-N,N-dimethylbenzylamine

Base Information

• Chemical Name: 4-Methoxy-N,N-dimethylbenzylamine
• CAS No.: 15175-54-9
• Molecular Formula: C10H15 N O
• Molecular Weight: 165.235
• NSC Number: 62160
• DSSTox Substance ID: DTXSID40289599
• Nikkaji Number: J590.655E
• Wikidata: Q82026967
• Mol file: 15175-54-9.mol

Synonyms:4-Methoxy-N,N-dimethylbenzylamine;15175-54-9;1-(4-methoxyphenyl)-N,N-dimethylmethanamine;Benzenemethanamine, 4-methoxy-N,N-dimethyl-;BENZENEMETHANAMINE,4-METHOXY-N,N-DIMETHYL-;NSC62160;SCHEMBL385286;4-Methoxy-N,N-dimethylbenzylamin;DTXSID40289599;n,n-dimethyl-4-methoxybenzylamine;(4-Methoxy-benzyl)-dimethyl-amine;AMY24277;NSC-62160;N,N-dimethyl-N-(4-methoxybenzyl)amine;(4-Methoxyphenyl)-N,N-dimethylmethanamine #;A18233

Chemical Property of 4-Methoxy-N,N-dimethylbenzylamine

Chemical Property:

• Vapor Pressure: 0.149mmHg at 25°C
• Boiling Point: 215.3°Cat760mmHg
• Flash Point: 61.7°C
• PSA: 12.47000
• Density: 0.971g/cm³
• LogP: 1.75680
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 165.115364102
• Heavy Atom Count: 12
• Complexity: 117

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CC1=CC=C(C=C1)OC

Technology Process of 4-Methoxy-N,N-dimethylbenzylamine

There total 36 articles about 4-Methoxy-N,N-dimethylbenzylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N,N-dimethyl-4-methoxybenzamide (7291-00-1) → N,N-dimethyl-4-methoxylbenzylamine (15175-54-9)

Guidance literature:

With 1,2-bis(dimethylsilyl)benzene; C₁₇H₂₈FeO₂S₂Si₂; In toluene; at 100 ℃; for 16h; Reagent/catalyst; Temperature; Time; Inert atmosphere;

Reference yield: 98.0%

methanol (67-56-1) + 4-methoxy-benzylamine (2393-23-9) → N,N-dimethyl-4-methoxylbenzylamine (15175-54-9)

Guidance literature:

With cesiumhydroxide monohydrate; (1,4-dimethyl-5,7-diphenyl-1,2,3,4-tetrahydro-6H-cyclopenta[b]pyrazin-6-one) irontricarbonyl complex3; hydrogen; at 110 ℃; under 7600.51 Torr; Autoclave;

DOI:10.1021/acs.orglett.8b02080

Reference yield: 95.0%

methanol (67-56-1) + 4-methoxybenzonitrile (874-90-8) → N,N-dimethyl-4-methoxylbenzylamine (15175-54-9)

Guidance literature:

With C₅₄H₄₃ClN₃P₂Ru⁽¹⁺⁾*F₆P^(1-); potassium tert-butylate; at 140 ℃; for 24h;

DOI:10.1021/acscatal.8b00021

upstream raw materials:

N,N-dimethyl-4-methoxybenzamide

formic acid

4-methoxy-benzaldehyde

N,N-dimethyl-formamide

Downstream raw materials:

p-methoxybenzyl butyrate

C₁₀H₁₄⁽²⁾HNO

4-methoxy-benzaldehyde

1-(4-methoxyphenyl)-N,N,N-trimethylmethanaminium iodide