5'-fluoro-2'-Iodoacetophenone

Base Information

Chemical Name:5'-fluoro-2'-Iodoacetophenone
CAS No.:914225-70-0
Molecular Formula:C8H6FIO
Molecular Weight:264.038
Hs Code.:2914700090
Mol file:914225-70-0.mol

Synonyms:1-(5-Fluoro-2-iodophenyl)ethanone

Suppliers and Price of 5'-fluoro-2'-Iodoacetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(5-Fluoro-2-iodophenyl)ethanone
2.5g
$ 155.00

Matrix Scientific
5'-Fluoro-2'-iodoacetophenone 95%
1g
$ 681.00

Matrix Scientific
5'-Fluoro-2'-iodoacetophenone 95%
5g
$ 2043.00

Crysdot
1-(5-Fluoro-2-iodophenyl)ethanone 98%
25g
$ 310.00

Chemenu
1-(5-Fluoro-2-iodophenyl)ethanone 95+%
25g
$ 299.00

Chemenu
1-(5-Fluoro-2-iodophenyl)ethanone 95+%
100g
$ 795.00

American Custom Chemicals Corporation
2'-IODO-5'-FLUOROACETOPHENONE 95.00%
5G
$ 1249.13

American Custom Chemicals Corporation
2'-IODO-5'-FLUOROACETOPHENONE 95.00%
250MG
$ 130.20

Alfa Aesar
5'-Fluoro-2'-iodoacetophenone, 97%
1g
$ 73.80

Alfa Aesar
5'-Fluoro-2'-iodoacetophenone, 97%
5g
$ 264.00

Total 73 raw suppliers

Chemical Property of 5'-fluoro-2'-Iodoacetophenone

Chemical Property:

Boiling Point:269.5 °C at 760 mmHg
Flash Point:116.8 °C
PSA：17.07000
Density:1.793 g/cm³
LogP:2.63290
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Sensitive.:Light Sensitive
Water Solubility.:Slightly soluble in water.

Purity/Quality:

99% ^*data from raw suppliers

1-(5-Fluoro-2-iodophenyl)ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 5'-Fluoro-2'-iodoacetophenone is used as pharmaceutical intermediates.

Technology Process of 5'-fluoro-2'-Iodoacetophenone

There total 5 articles about 5'-fluoro-2'-Iodoacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2343-25-1
5-fluoro-2-amino-acetophenone

: 914225-70-0
1-(5-fluoro-2-iodophenyl)ethan-1-one

Guidance literature:: 5-fluoro-2-amino-acetophenone; With hydrogenchloride; potassium nitrite; In water; at 5 - 10 ℃; for 0.5h;

With potassium iodide; In water; at 5 - 60 ℃; for 12h; Temperature; Reagent/catalyst;

Reference yield:

: 52548-63-7
5-fluoro-2-iodobenzoic acid

: 105-53-3
diethyl malonate

: 914225-70-0
1-(5-fluoro-2-iodophenyl)ethan-1-one

Guidance literature:: 5-fluoro-2-iodobenzoic acid; With thionyl chloride; at 60 ℃; Large scale;

diethyl malonate; With magnesium chloride; In ethyl acetate; at 20 ℃; for 0.5h; Large scale;

With triethylamine; In ethyl acetate; at 5 - 10 ℃; for 2.5h; Concentration; Temperature; Large scale;

Reference yield:

: 1261781-96-7
5-fluoro-2-iodobenzoyl chloride

: 108-59-8
malonic acid dimethyl ester

: 914225-70-0
1-(5-fluoro-2-iodophenyl)ethan-1-one

Guidance literature:: malonic acid dimethyl ester; With triethylamine; magnesium chloride; In acetonitrile; at 0 ℃; for 0.75h;

C₇H₃ClFIO; In acetonitrile; at 20 ℃; for 3h;

With lithium chloride; In water; N,N-dimethyl-formamide; at 100 ℃; for 4h;
DOI:10.1002/anie.201706418