LX-1606 Hippurate

Base Information

Chemical Name:LX-1606 Hippurate
CAS No.:1033805-22-9
Molecular Formula:C27H26ClF3N6O3
Molecular Weight:574.99
Hs Code.:
Mol file:1033805-22-9.mol

Synonyms:Telotristat ethyl;

Suppliers and Price of LX-1606 Hippurate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
TelotristatEthyl
10mg
$ 130.00

Matrix Scientific
(S)-Ethyl 2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate 95%
5mg
$ 556.00

Matrix Scientific
(S)-Ethyl 2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate 95%
10mg
$ 926.00

ChemScene
Telotristatethyl 99.68%
5mg
$ 156.00

ChemScene
Telotristatethyl 99.68%
50mg
$ 960.00

ChemScene
Telotristatethyl 99.68%
10mg
$ 288.00

Chemenu
LX1606 98%
50mg
$ 524.00

Biorbyt Ltd
LX1606 Hippurate >98%
100 mg
$ 542.30

Biorbyt Ltd
LX1606 Hippurate >98%
1000 mg
$ 2023.00

Biorbyt Ltd
LX1606 Hippurate >98%
250 mg
$ 986.00

Total 38 raw suppliers

Chemical Property of LX-1606 Hippurate

Chemical Property:

Appearance/Colour:white solid
Boiling Point:704.7±70.0 °C(Predicted)
PKA:6.72±0.33(Predicted)
PSA：131.17000
Density:1.42
LogP:6.27010
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99%, ^*data from raw suppliers

TelotristatEthyl ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Telotristat Ethyl can be used in biological study of serotonin biosynthesis as a predictive marker of serotonin pharmacodynamics and disease-induced dysregulation.

Technology Process of LX-1606 Hippurate

There total 4 articles about LX-1606 Hippurate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 67-56-1
methanol

: 1033805-28-5
(S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)-phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoic acid

: 1033805-22-9
(2S)-2-amino-3-[4-[2-amino-6-[[(1R)-1-[4-chloro-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethyl]oxy]pyrimidin-4-yl]phenyl]propionic acid ethyl ester

Guidance literature:: methanol; With thionyl chloride; at 0 - 5 ℃;

(S)-2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)-phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoic acid; In ethanol; at 40 - 45 ℃; for 6 - 12h;

With water; sodium carbonate; pH=6.5;