Technology Process of 12-phenylisoindolo[2,1-b]isoquinoline-5,7-dione
There total 4 articles about 12-phenylisoindolo[2,1-b]isoquinoline-5,7-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dimethyl zinc(II); palladium diacetate; lithium tert-butoxide;
In
N,N-dimethyl-formamide; toluene;
at 150 ℃;
for 20h;
under 760.051 Torr;
Reagent/catalyst;
Solvent;
regioselective reaction;
Catalytic behavior;
Mechanism;
Schlenk technique;
Sealed tube;
DOI:10.1002/adsc.201900305
- Guidance literature:
-
Multi-step reaction with 2 steps
1: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate / chlorobenzene / 16 h / 60 °C / Schlenk technique
2: silver trifluoroacetate; palladium diacetate; sodium carbonate / chlorobenzene / 15 h / 120 °C / 760.05 Torr / Schlenk technique
With
dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate; palladium diacetate; silver trifluoroacetate; sodium carbonate;
In
chlorobenzene;
DOI:10.1002/adsc.201800347
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium carbonate / ethyl acetate; water / 0 - 20 °C
2: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; cesium acetate / methanol / 16 h / 60 °C / Schlenk technique; Inert atmosphere; Sealed tube
3: palladium diacetate; lithium tert-butoxide; dimethyl zinc(II) / N,N-dimethyl-formamide; toluene / 20 h / 150 °C / 760.05 Torr / Schlenk technique; Sealed tube
With
dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; dimethyl zinc(II); cesium acetate; palladium diacetate; potassium carbonate; lithium tert-butoxide;
In
methanol; water; ethyl acetate; N,N-dimethyl-formamide; toluene;
DOI:10.1002/adsc.201900305
