PF-9366

Base Information

Chemical Name:PF-9366
CAS No.:72882-78-1
Molecular Formula:C₂₀H₁₉ClN₄
Molecular Weight:350.851
Hs Code.:
Mol file:72882-78-1.mol

Synonyms:

Suppliers and Price of PF-9366

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
PF-9366
10mg
$ 825.00

DC Chemicals
PF-9366 >98%
250 mg
$ 1000.00

CSNpharm
PF-9366
50mg
$ 736.00

CSNpharm
PF-9366
5mg
$ 120.00

CSNpharm
PF-9366
1mg
$ 71.00

Cayman Chemical
PF-9366
25mg
$ 281.00

Cayman Chemical
PF-9366
5mg
$ 71.00

Cayman Chemical
PF-9366
10mg
$ 135.00

Biosynth Carbosynth
PF 9366 NEW
10 mg
$ 125.00

Biosynth Carbosynth
PF 9366 NEW
50 mg
$ 437.50

Total 15 raw suppliers

Chemical Property of PF-9366

Chemical Property:

Melting Point:182-183.5 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
PKA:8.75±0.28(Predicted)
Density:1.25±0.1 g/cm3(Predicted)
Storage Temp.:2-8°C
Solubility.:Soluble in DMSO (up to 20 mg/ml).

Purity/Quality:

99%, ^*data from raw suppliers

PF-9366 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description PF-9366 (72882-78-1) is an allosteric inhibitor (IC50?= 420 nM) of methionine adenosyltransferase 2A (Mat2A), the primary enzyme responsible for extrahepatic synthesis of S-adenosyl-L-methionine (SAM).1?It inhibited cellular SAM production in H520 lung and Huh-7 liver cancer cells with IC50’s of 1.2 μM and 225 nM respectively.
Uses PF-9366 is a novel inhibitor of human methionine adenosyltransferase 2A (Mat2A), the extrahepatic isoform.

Technology Process of PF-9366

There total 1 articles about PF-9366 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.6%