2-(4-Methoxyphenyl)-5-nitro-1,3-benzoxazole

Base Information

• Chemical Name: 2-(4-Methoxyphenyl)-5-nitro-1,3-benzoxazole
• CAS No.: 1033-85-8
• Molecular Formula: C14H10N2O4
• Molecular Weight: 270.244
• DSSTox Substance ID: DTXSID40360155
• Nikkaji Number: J503.782D
• Wikidata: Q82141746
• ChEMBL ID: CHEMBL1304861
• Mol file: 1033-85-8.mol

Synonyms:2-(4-methoxyphenyl)-5-nitro-1,3-benzoxazole;STK016061;1033-85-8;HMS2685D24;MLS000717681;CHEMBL1304861;DTXSID40360155;REGID_for_CID_1084687;AKOS000636674;SMR000287427;SR-01000363699;SR-01000363699-1

Chemical Property of 2-(4-Methoxyphenyl)-5-nitro-1,3-benzoxazole

Chemical Property:

• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 270.06405680
• Heavy Atom Count: 20
• Complexity: 352

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C2=NC3=C(O2)C=CC(=C3)[N+](=O)[O-]

Technology Process of 2-(4-Methoxyphenyl)-5-nitro-1,3-benzoxazole

There total 8 articles about 2-(4-Methoxyphenyl)-5-nitro-1,3-benzoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

4-methoxy-benzaldehyde (123-11-5) + 2-hydroxy-5-nitroaniline (99-57-0) → 2-(4'-methoxyphenyl)-5-nitrobenzoxazole (1033-85-8)

Guidance literature:

In neat (no solvent); at 140 ℃; for 5h;

DOI:10.1039/c7cy01668a

Reference yield: 87.0%

S-methyl 3-oxo-3-(4-methoxylphenyl)propanedithioate (213468-59-8) + 2-hydroxy-5-nitroaniline (99-57-0) → 2-(4'-methoxyphenyl)-5-nitrobenzoxazole (1033-85-8)

Guidance literature:

With toluene-4-sulfonic acid; In neat (no solvent); at 90 ℃; for 14h;

DOI:10.1016/j.tet.2016.12.073

Reference yield: 85.0%

6-fluoro-3-nitroaniline (369-36-8) + 4-methoxy-benzoyl chloride (100-07-2) → 2-(4'-methoxyphenyl)-5-nitrobenzoxazole (1033-85-8)

Guidance literature:

With potassium carbonate; In neat (no solvent); at 130 ℃; for 12h;

DOI:10.1016/j.jfluchem.2014.02.013

upstream raw materials:

2-(4-methoxy-benzylidenamino)-4-nitro-phenol

4-methoxy-benzaldehyde

2-hydroxy-5-nitroaniline

4-hydroxy-benzaldehyde

Downstream raw materials:

2-(4-methoxyphenyl)benzo[d]oxazol-5-amine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1033-85-8 Benzoxazole, 2-(4-methoxyphenyl)-5-nitro-

Send

Send

Metric Ton KG G Pound L ML

Send

Send