3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-

Base Information

Chemical Name:3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-
CAS No.:1919837-50-5
Molecular Formula:C₁₆H₂₅BN₄O₄S
Molecular Weight:380.276
Hs Code.:
Mol file:1919837-50-5.mol

Synonyms:

Suppliers and Price of 3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(1-(Ethylsulfonyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile 97%
250mg
$ 225.00

Crysdot
2-(1-(Ethylsulfonyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile 97%
1g
$ 490.00

American Custom Chemicals Corporation
2-[1-(ETHANESULFONYL)-3-[4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1H-PYRAZOL-1-YL]AZETIDIN-3-YL]ACETONITRILE 95.00%
5MG
$ 453.50

Aaron Chemicals
2-[1-(ethanesulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]azetidin-3-yl]acetonitrile 98%
1g
$ 496.00

Total 16 raw suppliers

Chemical Property of 3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-

Chemical Property:

Boiling Point:572.6±60.0 °C(Predicted)
PKA:2.63±0.19(Predicted)
Density:1.27±0.1 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

2-(1-(Ethylsulfonyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidin-3-yl)acetonitrile 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]-

There total 11 articles about 3-Azetidineacetonitrile, 1-(ethylsulfonyl)-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.8%

: 269410-08-4
pyrazole-4-boronic acid pinacol ester

: 1187595-85-2
2-[1-(ethanesulfonyl)azetidin-3-ylidene]acetonitrile

: 1919837-50-5
2-(1-(ethanesulfonyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidine-3-yl)acetonitrile

Guidance literature:: With N,N,N′,N′-tetramethyl-N″-tert-butylguanidine; In tetrahydrofuran; at 65 ℃; for 3h; Solvent; Reagent/catalyst; Temperature;

Reference yield: 85.0%

: 2-(3-(4-bromo-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile

: 73183-34-3
bis(pinacol)diborane

: 1919837-50-5
2-(1-(ethanesulfonyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidine-3-yl)acetonitrile

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In tetrahydrofuran; at 60 - 65 ℃; Inert atmosphere;

Reference yield: 76.0%

: 1195-66-0
2-methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: C₁₀H₁₃IN₄O₂S

: 1919837-50-5
2-(1-(ethanesulfonyl)-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)azetidine-3-yl)acetonitrile

Guidance literature:: C₁₀H₁₃IN₄O₂S; With isopropyl magnesium chloride - lithium chloride complex; In tetrahydrofuran; at -10 - 0 ℃; Inert atmosphere;

2-methoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; In tetrahydrofuran; at 20 ℃; Inert atmosphere;