1,2,3-Butanetriol, 2-(2,4-difluorophenyl)-, [S-(R*,R*)]-

Base Information

• Chemical Name: 1,2,3-Butanetriol, 2-(2,4-difluorophenyl)-, [S-(R*,R*)]-
• CAS No.: 138457-41-7
• Molecular Formula: C₁₀H₁₂F₂O₃
• Molecular Weight: 218.2
• DSSTox Substance ID: DTXSID701200294
• Nikkaji Number: J2.780.657K

Synonyms:DTXSID701200294;138457-41-7;1,2,3-Butanetriol, 2-(2,4-difluorophenyl)-, [S-(R*,R*)]-

Chemical Property of 1,2,3-Butanetriol, 2-(2,4-difluorophenyl)-, [S-(R*,R*)]-

Chemical Property:

• XLogP3: 0.2
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 218.07545056
• Heavy Atom Count: 15
• Complexity: 215

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C(CO)(C1=C(C=C(C=C1)F)F)O)O
• Isomeric SMILES: C[C@@H]([C@@](CO)(C1=C(C=C(C=C1)F)F)O)O

Technology Process of 1,2,3-Butanetriol, 2-(2,4-difluorophenyl)-, [S-(R*,R*)]-

There total 10 articles about 1,2,3-Butanetriol, 2-(2,4-difluorophenyl)-, [S-(R*,R*)]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

1-(4-(2,4-difluorophenyl)-2,2-dimethyl-1,3-dioxolan-4-yl)ethanol (1202852-83-2) → (2RS,3SR)-2-(2,4-difluorophenyl)butane-1,2,3-triol + (2R*,3R*)-2-(2,4-Difluorophenyl)-1,2,3-butanetriol (126918-20-5,132563-67-8,138457-41-7)

Guidance literature:

With hydrogenchloride; water; acetic acid; In tetrahydrofuran; at 40 ℃;

DOI:10.1016/j.tetasy.2009.09.024

Reference yield:

(2S,3S)-2-(2,4-Difluoro-phenyl)-3-(tetrahydro-pyran-2-yloxy)-butane-1,2-diol (126918-19-2,132563-82-7) → (2R*,3R*)-2-(2,4-Difluorophenyl)-1,2,3-butanetriol (126918-20-5,132563-67-8,138457-41-7)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; for 0.5h; Yield given; Ambient temperature;

DOI:10.1248/cpb.38.2476

Reference yield:

(2S,3S)-2-(2,4-Difluoro-phenyl)-3-(tetrahydro-pyran-2-yloxy)-butane-1,2-diol (126918-19-2,132563-82-7) → (2S,3S)-2-(2,4-difluorophenyl)butane-1,2,3-triol (138457-41-7)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; Yield given; Ambient temperature;

DOI:10.1248/cpb.39.2241

upstream raw materials:

(2S,3S)-2-(2,4-Difluoro-phenyl)-3-(tetrahydro-pyran-2-yloxy)-butane-1,2-diol

1-(2,4-difluorophenyl)-2-(tetrahydropyranyloxy)propan-1-one

(2S^*,3R^*)-2-(2,4-Difluorophenyl)-1-(dimethylisopropoxysilyl)-3-(tetrahydropyran-2-yloxy)-2-butanol

1-(4-(2,4-difluorophenyl)-2,2-dimethyl-1,3-dioxolan-4-yl)ethanol

Downstream raw materials:

(2R^*,3R^*)-2-(2,4-Difluorophenyl)-1,3-bis(methanesulfonyloxy)-2-butanol

(2R,3R)-2-(2,4-difluorophenyl)-2-hydroxybutane-1,3-diyl diacetate

(2S,3S)-2-(2,4-difluorophenyl)-2-hydroxybutane-1,3-diyl diacetate

(2S,3R)-2-(2,4-difluorophenyl)-3-methyl-2-<(1H-1,2,4-triazol-1-yl)methyl>oxirane

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 138457-41-7 (2S,3S)-2-(2,4-difluorophenyl)butane-1,2,3-triol

Send

Send

Metric Ton KG G Pound L ML

Send

Send