4-ferrocenylbenzyl-1H-imidazole-1-carboxylate

Base Information

• Chemical Name: 4-ferrocenylbenzyl-1H-imidazole-1-carboxylate
• CAS No.: 1157854-68-6
• Molecular Formula: C₂₁H₁₈FeN₂O₂
• Molecular Weight: 386.233
• Mol file: 1157854-68-6.mol

Synonyms:

Chemical Property of 4-ferrocenylbenzyl-1H-imidazole-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-ferrocenylbenzyl-1H-imidazole-1-carboxylate

There total 1 articles about 4-ferrocenylbenzyl-1H-imidazole-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

(p-(hydroxymethyl)phenyl)ferrocene + 1,1'-carbonyldiimidazole (530-62-1) → 4-ferrocenylbenzyl-1H-imidazole-1-carboxylate (1157854-68-6)

Guidance literature:

In dichloromethane; mixt. of Fe complex and N,N'-carbonyldiimidazole in anhyd. CH2Cl2 heatedunder reflux for ca. 1 h; cooled; concd.; column chromd. (silica gel, Et2O); elem. anal.;

DOI:10.1016/j.jorganchem.2008.12.041

Reference yield: 90.0%

methanol (67-56-1) + 4-ferrocenylbenzyl-1H-imidazole-1-carboxylate (1157854-68-6) → (4-(methoxymethyl)phenyl)ferrocene (1157854-85-7)

Guidance literature:

In methanol; water; Fe complex in MeOH-H2O heated under reflux with stirring overnight; cooled; extd. with CH2Cl2; org. extracts dried (anhyd. Na2SO4); concd.; subjected to column chromy. (silica gel, hexane-Et2O 3:1); solvent removed undervac.;

DOI:10.1016/j.jorganchem.2008.12.041

Reference yield: 83.0%

potassium tetrachloroplatinate(II) (10025-99-7) + 4-ferrocenylbenzyl-1H-imidazole-1-carboxylate (1157854-68-6) + water (7732-18-5) → (p-(hydroxymethyl)phenyl)ferrocene + bis(4-ferrocenylbenzyl)carbonate (1157854-99-3) + dichlorobis(4-ferrocenylbenzyl-1H-imidazole-1-carboxylate)platinum

Guidance literature:

In dichloromethane; water; soln. of Fe complex in CH2Cl2 added to aq. soln. of K2PtCl4; stirred at room temp. for 72 h; org. layer sepd.; washed with H2O; dried (MgSO4); concd.; sepd. by column chromy. (silica gel, hexane-ether 1:1, ether);

DOI:10.1016/j.jorganchem.2008.12.041

upstream raw materials:

1,1'-carbonyldiimidazole

Downstream raw materials:

bis(4-ferrocenylbenzyl)carbonate

4-ferrocenylbenzylacetate

(4-(propoxymethyl)phenyl)ferrocene

(4-(butoxymethyl)phenyl)ferrocene