C₂₁H₂₅N₅O₂S

Base Information

Chemical Name:C₂₁H₂₅N₅O₂S
CAS No.:885618-05-3
Molecular Formula:C₂₁H₂₅N₅O₂S
Molecular Weight:411.528
Hs Code.:

C<sub>21</sub>H<sub>25</sub>N<sub>5</sub>O<sub>2</sub>S

Synonyms:

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Chemical Property of C₂₁H₂₅N₅O₂S

Chemical Property:

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Technology Process of C₂₁H₂₅N₅O₂S

There total 4 articles about C₂₁H₂₅N₅O₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 885617-10-7
tert-butyl 4-((2-(3-hydroxyphenyl)-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazine-1-carboxylate

: 885618-05-3
C₂₁H₂₅N₅O₂S

Guidance literature:: With hydrogenchloride; methanol; In 1,4-dioxane; dichloromethane; at 20 ℃; for 3h;
DOI:10.1021/jm3008745

Reference yield:

: C₂₀H₂₆ClN₅O₄S

: 885618-05-3
C₂₁H₂₅N₅O₂S

Guidance literature:: Multi-step reaction with 3 steps

1: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 10 h / 20 °C

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; toluene; ethanol / 1 h / 120 °C / Inert atmosphere

3: hydrogenchloride; methanol / dichloromethane; 1,4-dioxane / 3 h / 20 °C

With hydrogenchloride; methanol; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium tris(acetoxy)borohydride; sodium carbonate; In 1,4-dioxane; ethanol; dichloromethane; water; 1,2-dichloro-ethane; toluene; 2: |Suzuki Coupling;
DOI:10.1021/jm3008745

Reference yield:

: 885618-31-5
2-chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehyde

: 885618-05-3
C₂₁H₂₅N₅O₂S

Guidance literature:: Multi-step reaction with 4 steps

1: acetic acid / 1,2-dichloro-ethane / 2 h / 20 °C

2: sodium tris(acetoxy)borohydride / 1,2-dichloro-ethane / 10 h / 20 °C

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / water; toluene; ethanol / 1 h / 120 °C / Inert atmosphere

4: hydrogenchloride; methanol / dichloromethane; 1,4-dioxane / 3 h / 20 °C

With hydrogenchloride; methanol; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium tris(acetoxy)borohydride; sodium carbonate; acetic acid; In 1,4-dioxane; ethanol; dichloromethane; water; 1,2-dichloro-ethane; toluene; 3: |Suzuki Coupling;
DOI:10.1021/jm3008745